Portal tract in a case of chronic ductopenic rejection contains a hepatic artery and portal vein
but no interlobular bile duct.
![image](/wp-content/uploads/2017/04/image02276.jpeg)
Medium-sized muscular artery shows intimal foam cell arteriopathy
![image](/wp-content/uploads/2017/04/image02274-1.jpeg)
![image](/wp-content/uploads/2017/04/image02277.jpeg)
Centrilobular hepatocellular necrosis
![image](/wp-content/uploads/2017/04/image02278.jpeg)
![image](/wp-content/uploads/2017/04/image02279.jpeg)
PAS stain with diastase digestion in a case of chronic rejection shows the presence of hepatic arterioles
![image](/wp-content/uploads/2017/04/image02274-2.jpeg)
![image](/wp-content/uploads/2017/04/image02275-1.jpeg)
CLINICAL ISSUES
Presentation
Treatment
• Early chronic rejection may respond to potent immunosuppressants such as tacrolimus, OKT3, mycophenolate, or rapamycin
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