Because migraine is the most serious and common type of headache in patients afflicted with a headache disorder, it is the main focus of the discussion. The chapter closes with…

Figure 37–1 Sites of action of antimicrobial drugs. Antimicrobial drugs include cell wall synthesis inhibitors, protein synthesis inhibitors, metabolic and nucleic acid inhibitors (e.g., inhibitors of folate synthesis, DNA gyrase,…

Figure 5–1 Neurotransmission in the autonomic and somatic nervous systems. The parasympathetic nervous system consists of cranial and sacral nerves with long preganglionic and short postganglionic fibers. The sympathetic nervous…

Figure 4–1 Steps in the process of drug development in the United States. IND = investigational new drug; NDA = new drug application. Discovery and Characterization New drug compounds are…

Figure 7-1 Dose-dependent effects of atropine. Low doses of atropine inhibit salivation and sweating, and the magnitude of these effects increases as the dosage increases. Higher doses produce tachycardia, urinary…

Figure 1–1 Relationship between pharmacokinetics and pharmacodynamics. Toxicology Toxicology is the study of poisons and organ toxicity. It focuses on the harmful effects of drugs and other chemicals, and on…