Molecular Studies
Genetic alteration PTC FTC PDCa AC FA Comment BRAF V600E mutations 45 % (classic>tall cell variant>follicular variant) 20 % 20 % >90 % BRAF mutations BRAF K601E mutations 3 %…
PATHOLOGY & LABORATORY MEDICINE
Clinical and Radiologic Features
Signs and symptoms Percent patients Pulmonary Dyspnea [1, 7, 23, 24, 31, 47] 35–82 Pleural effusion [6, 7, 31, 85] 54–87 Chest pain [1, 7, 23, 24, 31, 47, 85]…
Immunohistochemistry
More likely to be positive in malignant mesothelioma P53 EMA GLUT-1 IMP3 Claimed to be positive in benign mesothelial proliferation Desmin Diffuse Malignant Mesothelioma Versus Other Malignancies Involving the Pleura…
Epidemiology
Fig. 2.1 Age-adjusted rates of malignant mesothelioma in the USA according to gender. (Adapted from SEER data) Fig. 2.2 Age-adjusted SEER incidence rates of mesothelioma from 1975–2009 according to gender…
Molecular Characteristics
Study Method Subtype Normal 3p 9p Chr. 22 Other Gibas 1986 Cytogenetics Epithelioid 1/8 (13 %) 4/8 (50 %) 3/8 (38 %)a Loss chr. 22 2/8 (25 %) Translocation 22q 1/8 (13 %) Biphasic 0/4…
Approaching the Diagnosis of Diffuse Malignant Mesothelioma
© Springer Science+Business Media New York 2015Timothy Craig Allen (ed.)Diffuse Malignant Mesothelioma10.1007/978-1-4939-2374-8_1 1. Approaching the Diagnosis of Diffuse Malignant Mesothelioma Timothy Craig Allen1 (1) Department of Pathology and Laboratory Medicine, The University of Texas Medical…
Diagnostic cytopathology of peritoneal washings
Chapter 7 Diagnostic cytopathology of peritoneal washings Rosemary E. Zuna TABLE OF CONTENTS INTRODUCTION 91 Specimen collection procedure 91 Interpretation approach 92 BENIGN CONDITIONS 92 Mesothelial cell polymorphism 92 Mesothelial…
Introduction
Chapter 1 Introduction Vinod B. Shidham TABLE OF CONTENTS PREAMBLE TO THE BOOK 1 HISTOLOGY AND GENERAL CYTOLOGY OF SEROUS CAVITY LINING 1 Histology 2 General cytology (with Papanicolaou and…
