Hereditary Paraganglioma/Pheochromocytoma Syndromes Vania Nosé, MD, PhD Graphic shows paraganglia and neuroendocrine tissues symmetrically distributed along the paravertebral axis in the abdomen, including the organ of Zuckerkandl and the adrenal…
Hereditary Pancreatic Cancer Syndrome Joel K. Greenson, MD This medium-power image from a patient with hereditary pancreatitis shows chronic pancreatitis with scar and atrophy of the acinar units . (Courtesy…
Familial Testicular Tumor Gladell P. Paner, MD Image shows mixed TGCT that consists of seminoma , embryonal carcinoma , and mature teratoma . In young adults, mixed TGCT is the…
Familial Paraganglioma-Pheochromocytoma Vania Nosé, MD, PhD Key Facts Terminology Syndromes characterized by susceptibility to pheochromocytoma and paraganglioma resulting from germline mutations in SDHB, SDHC, and SDHD Hereditary PGL/PCC should be…
Molecular Factors Index Molecular Factors Discussed Molecular Factor Chromosomal Location Definition/Alternative Names Chapters β-catenin (see CTNNB1) 10q, alterations of 10q Growth Hormone-producing Adenoma 10q11.2 10q11.2 RET Familial Thyroid Carcinoma; Multiple…
Antibody Index Antibodies Discussed Antibody Name/Symbol Antibody Description Clones/Alternative Names Chapters α1-antitrypsin alpha 1 antitrypsin A1AT Solid-Pseudopapillary Tumor of Pancreas α-fetoprotein alpha 1 fetoprotein AFP, Z5A06, Clone C3 Carney Complex…
Neurofibromatosis Type 1 Yaxia Zhang, MD, PhD Vania Nosé, MD, PhD Key Facts Terminology Autosomal dominant tumor disorder, which results from a mutation in NF1 gene Characterized by pigmentary or…
Protocol for the Examination of Specimens From Patients With Carcinoma of the Endocrine Pancreas Image Gallery
Protocol for the Examination of Specimens From Patients With Primary Pituitary Tumors Image Gallery Pituitary Gland, Sella, and Adjacent Structures (Left) The adenohypophysis is comprised of the pars tuberalis, pars…
Protocol for the Examination of Specimens From Patients With Carcinoma of the Adrenal Gland Image Gallery Tumor Staging Graphics (Left) Coronal graphic demonstrates T1 disease. The primary tumor is ≤…
