Multilocular Cystic Renal Cell Carcinoma Satish K. Tickoo, MD Victor E. Reuter, MD Key Facts Terminology Multilocular cystic renal cell carcinoma (MC-RCC) Renal cortical neoplasm composed of numerous clear cell-lined…
Papillary Adenoma Satish K. Tickoo, MD Victor E. Reuter, MD Key Facts Terminology Small epithelial proliferations with papillary, tubular, or tubulo-papillary configuration; ≤ 5 mm Etiology/Pathogenesis Trisomy 7 and 17,…
Familial Cancer Syndromes Satish K. Tickoo, MD Victor E. Reuter, MD Graphic representation of abdominal lesions in von Hippel-Lindau syndrome shows bilateral, multiple renal cysts , renal tumors , pancreatic…
Introduction to Kidney Tumors Satish K. Tickoo, MD Victor E. Reuter, MD The relationship of renal sinus soft tissues with renal parenchyma is depicted. Sinus fat invasion (pT3a) may occur…
Classification of Kidney Tumors & Tumor-like Lesions Satish K. Tickoo, MD NONNEOPLASTIC LESIONS Tumor-like Lesions Xanthogranulomatous pyelonephritis Renal malakoplakia Inflammatory myofibroblastic lesion/tumor Perirenal and sinus cysts NEOPLASMS Kidney Tumors in…
Metastatic Melanoma Elizabeth A. Montgomery, MD Key Facts Terminology Spread of malignant melanoma to gastrointestinal tract In contrast to rare primary melanomas that typically involve esophagus and anus Clinical Issues…
Hamartomatous Polyps, Peutz-Jeghers Amitabh Srivastava, MD Key Facts Terminology Peutz-Jeghers polyposis syndrome is characterized by mucocutaneous pigmentation, hamartomatous polyposis, and increased risk of cancer Etiology/Pathogenesis Germline mutation in LKB1/STK11 gene…
Hamartomatous Polyps, Juvenile Amitabh Srivastava, MD Key Facts Terminology Hamartomatous polyp that may occur sporadically or as part of polyposis syndrome Etiology/Pathogenesis Germline mutations in SMAD4 or BMPR1A present in…
Colchicine Effect Elizabeth A. Montgomery, MD Key Facts Terminology GI symptoms associated with mitotic arrest restricted to proliferative compartment of mucosa Best seen in small bowel and gastric antrum Clinical…
Paclitaxel (Taxol) Effect Elizabeth A. Montgomery, MD Key Facts Terminology Pattern of mitotic arrest and apoptosis of the gastrointestinal tract mucosa associated with administration of paclitaxel (Taxol) Clinical Issues Excellent…
