Inverted Papilloma Jesse K. McKenney, MD Key Facts Terminology Benign urothelial neoplasm with predominantly endophytic growth pattern Clinical Issues Very uncommon urothelial lesion (1% of urothelial neoplasms) Most common in…

Overview of Urinary Bladder Neoplasms Jesse K. McKenney, MD Mahesha Vankalakunti, MD The spectrum of neoplasia in the bladder includes noninvasive papillary urothelial carcinomas. These may progress to invasive urothelial…

Nephrogenic Adenoma Jesse K. McKenney, MD Mahul B. Amin, MD Key Facts Etiology/Pathogenesis Many are secondary to urothelial injury Clinical Issues Usually incidental microscopic findings May have irritative symptoms from…

Amyloidosis Jesse K. McKenney, MD Key Facts Terminology Deposition of amyloid protein in urinary bladder 2 types Primary localized process Systemic amyloidosis Microscopic Pathology Deposition of eosinophilic amorphous material in…

Immunohistochemistry, Kidney Rugvedita Parakh, MD Satish K. Tickoo, MD Victor E. Reuter, MD Renal Tumors with Clear/Light-Staining Cytoplasm Antibody Clear Cell RCC Chromophobe RCC MITF/TFE Family Translocation-associated Carcinoma Clear Cell…

Cystic Nephroma/Mixed Epithelial and Stromal Tumor Satish K. Tickoo, MD Victor E. Reuter, MD Key Facts Terminology Cystic nephroma (CN), mixed epithelial and stromal tumor (MEST) Multicystic to solid and…

Metastatic Tumors Satish K. Tickoo, MD Victor E. Reuter, MD Key Facts Terminology Involvement of kidney by tumors originating in other organs Direct extension from adjacent organs does not qualify…

Juxtaglomerular Cell Tumor (Reninoma) Satish K. Tickoo, MD Victor E. Reuter, MD Key Facts Terminology Tumors derived from juxtaglomerular apparatus cells of the kidney, often characterized by association with hyperreninism,…

Renomedullary Interstitial Cell Tumor Satish K. Tickoo, MD Victor E. Reuter, MD Key Facts Terminology Benign renal medullary neoplasm, arising from renomedullary interstitial cells Clinical Issues Most common kidney tumor…

Carcinoid Satish K. Tickoo, MD Victor E. Reuter, MD Key Facts Terminology Well-differentiated neuroendocrine neoplasm arising within kidney Etiology/Pathogenesis Up to 20% of primary renal carcinoids arise in “horseshoe” kidneys…