Urachal Adenocarcinoma
Urachal Adenocarcinoma Jesse K. McKenney, MD Key Facts Terminology Primary carcinoma of any morphologic subtype originating from urachus Clinical Issues Very rare Hematuria is most common symptom Mucusuria rarely seen…
PATHOLOGY & LABORATORY MEDICINE
Protocol for Urinary Bladder Cancer Specimens
Protocol for Urinary Bladder Cancer Specimens Urinary Bladder: Biopsy and Transurethral Resection of Bladder Tumor (TURBT) Surgical Pathology Cancer Case Summary (Checklist) Applies primarily to invasive carcinomas &/or associated epithelial…
Squamous Proliferations Other than Carcinoma
Squamous Proliferations Other than Carcinoma Jesse K. McKenney, MD Key Facts Etiology/Pathogenesis Keratinizing squamous metaplasia May be associated with chronic irritation Catheters, stones, or parasitic infection Neurogenic bladder Condyloma of…
Invasive Adenocarcinoma
Invasive Adenocarcinoma Jesse K. McKenney, MD Mahesha Vankalakunti, MD Key Facts Etiology/Pathogenesis Predisposing factors Associated with bladder exstrophy Nonfunctioning bladder Clinical Issues Rare primary bladder neoplasm (< 2% of bladder…
Invasive Urothelial Carcinoma
Invasive Urothelial Carcinoma Jesse K. McKenney, MD Key Facts Terminology Urothelial carcinoma that invades beyond basement membrane Clinical Issues Invasion into lamina propria usually managed with intravesical therapy Invasion into…
Cystitis Cystica and Glandularis
Cystitis Cystica and Glandularis Jesse K. McKenney, MD Key Facts Terminology Invaginated urothelial nests in superficial lamina propria with cystic dilatation forming luminal space Cystitis glandularis has luminal cuboidal or…
High-Grade Papillary Urothelial Carcinoma
High-Grade Papillary Urothelial Carcinoma Jesse K. McKenney, MD Mahul B. Amin, MD Key Facts Terminology Papillary urothelial neoplasm with moderate to marked nuclear atypia Clinical Issues Most occur in 6th…
Adenocarcinoma In Situ
Adenocarcinoma In Situ Jesse K. McKenney, MD Key Facts Terminology Noninvasive glandular lesion characterized by atypical columnar epithelium Also called “noninvasive urothelial carcinoma with glandular differentiation” and “urothelial carcinoma with…
Low-Grade Papillary Urothelial Carcinoma
Low-Grade Papillary Urothelial Carcinoma Jesse K. McKenney, MD Mahul B. Amin, MD Key Facts Terminology Papillary urothelial neoplasm with some degree of cytoarchitectural disorder and distinct but low-grade cytologic abnormality…
Villous Adenoma
Villous Adenoma Jesse K. McKenney, MD Key Facts Terminology Benign glandular neoplasm arising from urothelium Clinical Issues Presenting symptoms Hematuria and irritative bladder symptoms Rarely, mucosuria can be seen Therapy:…
