Keratocystic Odontogenic Tumor (Odontogenic Keratocyst) Brenda L. Nelson, DDS, MS Key Facts Terminology Odontogenic keratocyst (OKC) Distinct developmental odontogenic cyst that may be locally aggressive Etiology/Pathogenesis Arise from cells of…
Carcinoma Ex-Pleomorphic Adenoma Lester D. R. Thompson, MD Key Facts Terminology Presence of carcinoma arising from pleomorphic adenoma Clinical Issues Usually 6th to 7th decades, about 10 years older than…
Protocol for the Examination of Salivary Gland Specimens Lester D. R. Thompson, MD Major Salivary Glands Incisional Biopsy, Excisional Biopsy, Resection Specimen ___ Parotid gland ___ Superficial lobe only ___…
Cystadenocarcinoma (Papillary) Lester D. R. Thompson, MD Key Facts Terminology Malignant epithelial salivary gland neoplasm characterized by predominantly cystic growth with intraluminal papillae Clinical Issues Slowly growing, painless swelling or…
Lymphoepithelial Carcinoma Bruce M. Wenig, MD Key Facts Terminology Undifferentiated carcinoma with associated prominent nonneoplastic lymphoplasmacytic cell infiltrate Etiology/Pathogenesis Etiology linked to Epstein-Barr virus (EBV) Near 100% association in patients…
Pleomorphic Adenoma Brenda L. Nelson, DDS, MS Key Facts Terminology Synonym: Benign mixed tumor Benign epithelial tumor that shows epithelial, myoepithelial, and mesenchymal differentiation Clinical Issues Most common neoplasm of…
Sjogren Syndrome Kevin R. Torske, DDS, MS Lester D. R. Thompson, MD Key Facts Terminology Reactive, focal to diffuse lymphoid infiltrate of salivary glands leading to parenchymal atrophy and degeneration…
Chronic Sclerosing Sialadenitis Bruce M. Wenig, MD Key Facts Terminology Chronic fibroinflammatory salivary gland disease with characteristic morphology that may represent IgG4-associated disease Etiology/Pathogenesis Increasing evidence that CSS, if IgG4…
Protocol for the Examination of Lip and Oral Cavity Specimens Lester D. R. Thompson, MD Lip and Oral Cavity Incisional Biopsy, Excisional Biopsy, Resection Specimen (select all that apply) _…
