T-cell Prolymphocytic Leukemia Involving Lymph Node and Other Tissues Tariq Muzzafar, MBBS L. Jeffrey Medeiros, MD Key Facts Terminology T-PLL is aggressive disease characterized by Numerous small/medium-sized T prolymphocytes Involvement…
Primary Diffuse Large B-cell Lymphoma of the CNS Tariq Muzzafar, MBBS Key Facts Clinical Issues Neuropsychiatric signs and symptoms Raised intracranial pressure Intraocular involvement: blurred vision and floaters Image Findings…
Angiomyomatous Hamartoma Carlos E. Bueso-Ramos, MD, PhD Key Facts Terminology Benign smooth muscle proliferation that begins in hilum and extends into medulla and cortex of lymph node Involves inguinal lymph…
Extranodal NK-/T-cell Lymphoma, Nasal Type L. Jeffrey Medeiros, MD Key Facts Etiology/Pathogenesis EBV is constant finding, present in clonal episomal form, and is likely involved in pathogenesis Clinical Issues Nasal…
Plasmacytoma Pei Lin, MD Key Facts Terminology Plasmacytoma is a neoplasm composed of monoclonal plasma cells that involves tissues No evidence of bone marrow involvement No clinical or laboratory evidence…
Overview of Lymphoproliferative Disorders Associated with Primary Immune Deficiency Disorders Keyur Patel, MD, PhD Chronic granulomatous inflammation involving lymph node in a patient with common variable immunodeficiency (CVID). B-cell lymphoma…
Primary Cutaneous Anaplastic Large Cell Lymphoma C. Cameron Yin, MD, PhD Key Facts Terminology Cutaneous lymphoma composed of large T cells that express CD30 (> 75%) Clinical Issues Common sites:…
Lymphocyte-rich Classical Hodgkin Lymphoma Sa A. Wang, MD Key Facts Terminology Type of CHL in which small reactive lymphocytes predominate and are associated with HRS cells Clinical Issues 4-5% of…
Intravascular Large B-cell Lymphoma Francisco Vega, MD, PhD Key Facts Terminology Rare large B-cell lymphoma characterized by selective intravascular growth Clinical Issues Absence of marked lymphadenopathy Middle-aged or elderly patients…
Lymphomatoid Papulosis C. Cameron Yin, MD, PhD Key Facts Terminology Chronic, self-healing and recurrent erythematous papules/nodules on skin of trunk and extremities Clinical Issues Usually remains confined to skin Excellent…
