Common Acquired Melanocytic Nevi Christine J. Ko, MD Key Facts Clinical Issues Majority develop in adolescence Microscopic Pathology Flat surface to slightly raised to polypoid Epidermis varies (e.g., thin or…

Primary Cutaneous CD4+ Small/Medium Pleomorphic T-cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology T-cell lymphoma of skin with small to medium-sized CD4(+) T cells and usually indolent clinical course…

Mycosis Fungoides (and Subtypes) Sa A. Wang, MD Key Facts Terminology Primary cutaneous T-cell lymphoma characterized by Epidermotropism Clinical course showing stepwise evolution of patches, plaques, and tumors Clinical Issues…

Congenital Melanocytic Nevi Christine J. Ko, MD Key Facts Clinical Issues Present at birth, by definition However, some congenital melanocytic nevi may be “tardive” and not readily noticeable at birth…

Extranodal NK/T-cell Lymphoma, Nasal Type Aaron Auerbach, MD, PhD Key Facts Terminology Tumor of NK cells or T cells, with necrosis, Epstein-Barr virus infection, and angioinvasion Etiology/Pathogenesis Epstein-Barr virus Clinical…

Primary Cutaneous Anaplastic Large Cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology One of the primary cutaneous CD30(+) T-cell lymphoproliferative disorders T-cell lymphoma of atypical, usually large CD30(+) cells,…

Conventional Blue Nevi Soheil Sam Dadras, MD, PhD Key Facts Terminology Benign melanocytic tumor composed of spindle-shaped and dendritic melanocytes and melanophages Clinical Issues Occurs in any age, in wide…

Lymphomatoid Papulosis Aaron Auerbach, MD, PhD Key Facts Terminology One of the CD30(+) T-cell lymphoproliferative disorders Recurrent lymphoproliferative cutaneous disorder Disorder with self-healing lesions that regress without treatment and have…

Leukemia Cutis Jeremy C. Wallentine, MD Key Facts Terminology Clinically identifiable cutaneous lesions secondary to cutaneous infiltration by neoplastic leukocytes (myeloid or lymphoid) Clinical Issues Presentation may precede (aleukemic LC),…

Aggressive Epidermotropic CD8+ Cytotoxic T-cell Lymphoma Aaron Auerbach, MD, PhD Key Facts Terminology Provisional diagnosis in the 2008 WHO, T-cell lymphoma consisting of CD8(+) cytotoxic αβ T cells in epidermis,…