Sclerosing Epithelioid Fibrosarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Fibrosarcoma variant characterized by at least focal epithelioid cytomorphology and areas of dense fibrosis Clinical Issues Around periosteum or…
Low-Grade Fibromyxoid Sarcoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Malignant fibroblastic neoplasm composed of bland spindles in collagenous matrix, often with prominent collagenous nodules Characterized by specific translocations…
Myxofibrosarcoma Thomas Mentzel, MD Key Facts Terminology Myxofibrosarcoma represents a spectrum of malignant fibroblastic neoplasms with variably myxoid stroma and characteristic elongated curvilinear vessels Clinical Issues One of the most…
Myxoinflammatory Fibroblastic Sarcoma Elizabeth A. Montgomery, MD Key Facts Clinical Issues Slow-growing infiltrative mass usually affecting distal extremities (hands and feet) of adults Recurrences are common, but metastases are rare…
Adult-Type Fibrosarcoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Soft tissue sarcoma composed of fibroblasts Lacks features of named fibrosarcoma subtypes Etiology/Pathogenesis Exceptionally rare if strictly defined Microscopic Pathology…
Low-Grade Myofibroblastic Sarcoma Thomas Mentzel, MD Key Facts Terminology Low-grade myofibroblastic sarcoma represents distinct atypical myofibroblastic neoplasm with fibromatosis-like morphologic features Clinical Issues Occurs frequently in head and neck region…
Infantile Fibrosarcoma Thomas Mentzel, MD Key Facts Terminology Occurs in infants and young children; represents low-grade fibrosarcoma that carries favorable prognosis Clinical Issues Congenital or arises in 1st two years…
Solitary Fibrous Tumor Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology Fibroblastic mesenchymal tumor with prominent hemangiopericytic branching vascular pattern Initially described in pleura Occur in any location Closely related…
Fibromatosis Elizabeth A. Montgomery, MD Key Facts Terminology Palmar fibromatosis: Dupuytren contracture, Dupuytren disease Plantar fibromatosis: Ledderhose disease Penile fibromatosis: Peyronie disease Deep fibromatosis: Aggressive fibromatosis, desmoid tumor Myofibroblastic proliferations…
Lipofibromatosis Elizabeth A. Montgomery, MD Key Facts Clinical Issues Painless mass Hands and feet of children Median age: 1 year Male predominance (M:F = 2:1) Local recurrences common No metastases…
