Adult-Type Fibrosarcoma

Adult-Type Fibrosarcoma

Cyril Fisher, MD, DSc, FRCPath

This shows a typically cellular low-grade fibrosarcoma with uniform spindle cells arranged in long intersecting fascicles in a so-called herringbone pattern. No necrosis is seen.

This well-differentiated fibrosarcoma shows uniform tapered spindle cells. The nuclei are elongated, and some have a small nucleolus.



  • Soft tissue sarcoma composed of fibroblasts

  • Lacks features of named fibrosarcoma subtypes

  • Now very rare; mostly a diagnosis of exclusion

  • Pleomorphic variants are currently classified as undifferentiated sarcoma/malignant fibrous histiocytoma

  • Conclusive diagnosis can require electron microscopy


De Novo

  • Exceptionally rare if strictly defined

Arising in Course of Other Tumor

  • Fibrosarcoma in dermatofibrosarcoma

    • Probable origin of many superficial adult fibrosarcomas

  • Malignant solitary fibrous tumor

  • Component of other fibrosarcoma subtypes, e.g., sclerosing epithelioid fibrosarcoma

Jul 9, 2016 | Posted by in PATHOLOGY & LABORATORY MEDICINE | Comments Off on Adult-Type Fibrosarcoma
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