Epithelioid Hemangioma Steven D. Billings, MD Key Facts Terminology Angiolymphoid hyperplasia with eosinophilia, histiocytoid hemangioma Benign vascular tumor with epithelioid endothelial cells, usually accompanied by lymphoid aggregates and eosinophils Clinical…
Acquired Tufted Angioma David S. Cassarino, MD, PhD Key Facts Terminology Acquired tufted angioma (ATA) Angioblastoma (of Nakagawa) Multiple cannonball-like cellular collections of small vessels in dermis Clinical Issues Children…
Spindle Cell Hemangioma Steven D. Billings, MD Key Facts Terminology Formerly called spindle cell hemangioendothelioma Clinical Issues Subcutaneous mass Usually acral location Sometimes multifocal Associated with Mafucci syndrome in some…
Capillary, Venous, and Cavernous Hemangiomas Amitabh Srivastava, MD Key Facts Terminology Benign vascular tumors composed of blood vessels lined by plump to flattened endothelial cells with no atypia Etiology/Pathogenesis May…
Leiomyosarcoma Elizabeth A. Montgomery, MD Key Facts Terminology Malignant neoplasm composed of cells exhibiting smooth muscle differentiation Etiology/Pathogenesis Epstein-Barr virus-associated in immunosuppressed patients Clinical Issues Retroperitoneal and inferior vena cava…
Papillary Endothelial Hyperplasia Amitabh Srivastava, MD Key Facts Terminology Benign, reactive, intravascular papillary endothelial proliferation Clinical Issues Wide site distribution; located in deep dermis or subcutaneous tissue Macroscopic Features Small,…
Bacillary Angiomatosis David S. Cassarino, MD, PhD key Facts Terminology Reactive vascular proliferation associated with Bartonella (gram-negative coccobacilli) bacterial infection Etiology/Pathogenesis Most patients are immunocompromised, especially HIV/AIDS Also associated with…
Palisaded Myofibroblastoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign spindle cell tumor of modified smooth muscle cells in lymph node Clinical Issues Mainly inguinal region Mostly in males…
Deep Leiomyoma Cyril Fisher, MD, DSc, FRCPath Key Facts Clinical Issues Rare: 4% of benign soft tissue tumors Slow-growing mass Usually painless Deep subcutis or subfascial in limbs in either…
Sclerosing Pseudovascular Rhabdomyosarcoma David R. Lucas, MD Key Facts Terminology Variant of RMS characterized by extensive stromal fibrosis and pseudovascular, microalveolar, or cordlike architecture Clinical Issues Rare; only 34 reports…
