Organized Diffuse Alveolar Damage Alvaro C. Laga Abida K. Haque The organizing phase of diffuse alveolar damage (DAD) generally begins approximately 7 days after an acute lung injury, and is…

Diffuse Alveolar-Septal Amyloidosis Alvaro C. Laga Timothy C. Allen Philip T. Cagle Lung involvement as diffuse alveolar-septal amyloidosis occurs in most cases of systemic primary amyloidosis. Involvement limited to the…

Carcinomas Primary lung carcinomas account for the highest number of cancer deaths in the United States each year. Carcinomas are tumors of the lung epithelium, including the bronchial mucosa. The…

Airway-Centered Interstitial Fibrosis Timothy C. Allen Philip T. Cagle Several recent reports have proposed that interstitial pneumonia centered around small airways may be a form of idiopathic interstitial pneumonia not…

Flock Lung Armando E. Fraire Flocking is a widely used industrial process in which short segments of nylon or similar synthetic fibers are applied to backing fabric materials to produce…

Hot-Tub Lung Andras Khoor Hot-tub lung is a diffuse granulomatous interstitial lung disease that develops in immunocompetent individuals caused by inhalation of aerosolized nontuberculous mycobacteria (usually Mycobacterium avium complex), which…

Hypersensitivity Pneumonitis Roberto Barrios Keith M. Kerr Hypersensitivity pneumonitis, also known as hypersensitivity pneumonia and extrinsic allergic alveolitis, is a diffuse interstitial granulomatous pneumonia secondary to inhalation of organic antigens….

Infectious Interstitial Pneumonia Abida K. Haque Infectious interstitial pneumonia is most often the result of viral infection. Several viruses produce this pattern, in addition to causing airway inflammation and necrosis….

Respiratory Bronchiolitis-Associated Interstitial Lung Disease/Desquamative Interstitial Pneumonia Philip T. Cagle Respiratory bronchiolitis may uncommonly be associated with a generally mild and generally nonprogressive interstitial lung disease characterized by dyspnea, cough,…

Respiratory Bronchiolitis Philip T. Cagle Lesions of respiratory bronchiolitis may be observed involving occasional respiratory bronchioles in lung specimens from cigarette smokers unaccompanied by clinically significant findings. Less frequently, respiratory…