GENERAL SURGERY
Kinetics and dosing
4 Kinetics and dosing CHAPTER CONTENTS Absorption Bioavailability The substance administered The mode and route of administration The recipient Dermal administration The structure of the skin Percutaneous absorption Dermal dosing…
Constituent profiles
14 Constituent profiles CHAPTER CONTENTS Isomers Constituent profiles A–Z The purpose of these profiles is to provide safety information for essential oil constituents, all of which are referred to in…
The reproductive system
11 The reproductive system CHAPTER CONTENTS Reproductive toxicology Xenobiotics in pregnancy and lactation Fertility Female Fertility Estrogenic activity Dopaminergic activity Male Fertility Estrogenic and androgenic activity Other actions Conception Implantation…
The digestive system
9 The digestive system CHAPTER CONTENtS The gastrointestinal tract Dose-related effects Excipients The liver Hepatotoxicity Liver function tests Oxidative stress Visible lesions Fatty degeneration Porphyrin production Glutathione depletion Hepatocellular toxicity…
The nervous system
10 The nervous system CHAPTER CONTENTS Neurotoxicity Structural changes Phytol Functional effects CNS stimulant activity Convulsants Pinocamphone Thujone Camphor Pulegone Eucalyptus oil Fennel oil Turpentine oil Other reported cases Animal…
Essential oil profiles
13 Essential oil profiles CHAPTER CONTENTS Notes Information given in the profiles Regulatory guidelines GRAS EU allergens legislation IFRA guidelines Adjusting safe doses and concentrations The amount applied Combinations of…
The respiratory system
6 The respiratory system CHAPTER CONTENTS Volatile organic compounds Adverse effects of airborne substances Sensory irritation Terpene oxidation Thresholds Bronchial hyper-reactivity Transient receptor potential channels Respiratory disease Acute respiratory tract…
General safety guidelines
15 General safety guidelines CHAPTER CONTENTS First aid Signs and symptoms of toxicity Reporting adverse events Safety in healthcare Adverse skin reactions Child safety Patient safety Practitioner safety General safety…
