Deborah R. Simkin, MD CHAPTER102 CHAPTER OUTLINE ■    BIOPSYCHOSOCIAL ANALYSIS ■    STRESSORS ■    STUDIES OF INHERITABILITY ■    DEVELOPMENT OF THE ADOLESCENT BRAIN ■    DEVELOPMENT OF GOAL-DIRECTED BEHAVIOR ■    EVIDENCE FROM NEUROIMAGING STUDIES OF HUMAN DEVELOPMENT ■    BIOLOGIC…

Douglas M. Ziedonis, MD, MPHXiaoduo Fan, MD, MPH, MSAurelia N. Bizamcer, MD, PhDStephen A. Wyatt, DOMakenzie E. Tonelli, BADavid A. Smelson, PsyD CHAPTER88 CHAPTER OUTLINE ■    DEFINITION OF PSYCHOSIS ■    PREVALENCE OF…

Melissa Weddle, MD, MPHPatricia K. Kokotailo, MD, MPH CHAPTER100 CHAPTER OUTLINE ■    PREVALENCE AND TRENDS ■    MORE FREQUENT USE ■    MULTIPLE DRUG USE ■    CORRELATES OF SUBSTANCE USE ■    CONCLUSIONS Epidemiology has historically been defined…

Domenic A. Ciraulo, MDClifford M. Knapp, PhD CHAPTER 8 CHAPTER OUTLINE ■    FORMULATIONS AND CHEMICAL STRUCTURE ■    BRIEF HISTORICAL FEATURES ■    EPIDEMIOLOGY ■    PHARMACOKINETICS ■    PHARMACODYNAMICS ■    DRUG–DRUG INTERACTIONS ■    MECHANISM OF ADDICTION ■    ADDICTION LIABILITY ■    TOXICITY STATES…

Edward C. Covington, MDMargaret M. Kotz, DO CHAPTER98 CHAPTER OUTLINE ■    INTRODUCTION ■    SIGNIFICANCE ■    EPIDEMIC OF PRESCRIPTION OPIOID ABUSE ■    PROBLEMS OF COMORBIDITY ■    RED FLAGS FOR ADDICTION ■    TREATING PAIN IN THE PRESENCE OF…

Theodore V. Parran, Jr., MD, FACPRichard A. McCormick, PhDChristina M. Delos Reyes, MD CHAPTER20 CHAPTER OUTLINE ■    ASSESSMENT IN MANAGING PATIENTS WITH SUBSTANCE USE DISORDERS ■    NEEDS OF DIFFERENT ASSESSORS ■    TASKS OF…

Frederic C. Blow, PhDKristen L. Barry, PhD CHAPTER36 CHAPTER OUTLINE ■    SCOPE OF THE PROBLEM IN OLDER ADULTHOOD ■    BROAD-BASED ASSESSMENT OF SUBSTANCE USE PROBLEMS ■    BRIEF ALCOHOL INTERVENTIONS ■    BRIEF INTERVENTION CONTENT AND…

Stephen T. Higgins, PhDRyan Render, PhDThomas J. White, PhD CHAPTER58 CHAPTER OUTLINE ■    HISTORICAL PERSPECTIVE ■    TREATMENT MODEL ■    TREATMENT PLANNING ■    PRETREATMENT ISSUES ■    TREATMENT AND TECHNIQUE ■    EMPIRICAL SUPPORT ■     CONCLUSIONS Contingency management (CM)…

John J. Woodward, BS, MS, PhD CHAPTER 7 CHAPTER OUTLINE ■    DEFINITION ■    SUBSTANCES INCLUDED IN THIS CLASS ■    FORMULATIONS AND METHODS OF USE ■    CLINICAL USES ■    BRIEF HISTORICAL FEATURES ■    EPIDEMIOLOGY ■    PHARMACOKINETICS ■    PHARMACODYNAMICS ■    DRUG–DRUG…

Michael F. Weaver, MD, FASAMHendrée E. Jones, PhDMartha J. Wunsch, MD, FAAP, FASAM CHAPTER83 CHAPTER OUTLINE ■    APPROACH TO THE PREGNANT WOMAN ■    NEONATAL ABSTINENCE SYNDROMES ■    TOBACCO ■    ALCOHOL AND SEDATIVES ■    OPIOIDS ■    CANNABIS…