Fig. 23.1 a Fluorescence imaging of MSN-NH2-FITC (left) and MSN-ICG (middle) in anesthetized rats before and 90 min after i.v. injection. Scanning time was all set to be 30 s. The fluorescence image…
Fig. 35.1 Examples of unnatural peptidomimetics As they are not based on regular peptide backbones, they are often much more stable against proteolysis and have improved bioavailability compared to peptide counterparts…
Fig. 31.1 State-of-the-art medical linear accelerator (a) and a patient dose distribution generated by a treatment technique called RapidArc (b). Small animal conformal radiotherapy system at Stanford University based on a…
Engineered nanostructure Stem cell Differentiated cell Proposed mechanism Reference LBL-assembled SWCNT/PEI polyelectrolyte composite mNSCs Neurons, oligodendrocytes, astrocytes Chemical structure better suitable as neural electrode [36] LBL-assembled SWCNT/laminin composite mNSCs Neurons…
Fig. 12.1 Affibody-binding proteins: library and target binding. Illustration of the three-helix bundle affibody protein scaffold Z in band representation (green), with the 13 positions randomized during affibody protein library constructions…
Fig. 5.1 The types of neural scaffolds are shown on the left-hand side of the diagram, and the components of tissue-engineered nerve grafts are shown on the right-hand side. Adapted with…
Name Amino acids Topology Typical paratope Stability (T m , °C) Parental Binders Knottin 20–50 Knotted 3-disulfide core Loop 1 ~100 N.d. Affibody 58 Triple α-helical bundle 13 amino acids…
Fig. 20.1 Near-infrared (NIR) window tissue absorption coefficients. Between the wavelengths of approximately 700–900 nm, the oxygenated hemoglobin (OxyHb), deoxygenated hemoglobin (DeoxyHb), water, and lipid absorption spectra reach a minimum; this makes…
Fig. 18.1 Viral vector designs 18.2.1.1 Retroviral Vectors Retroviruses are enveloped RNA viruses of 80–130 nm in diameter with a genome size of 8–11 kilobases (kb) [11]. Retroviral genomes are made up…
Fig. 25.1 Examples of established delivery systems. Physical techniques such as electroporation and microinjection, viral vectors in the form of retrovirus or adenovirus, as well as non-viral vectors which include liposomes,…
