CHAPTER 23 Lipids: Bioactive Lipids and Lipid-Sensing Receptors CHAPTER OUTLINE Bioactive Lipids and Lipid-Sensing Receptors Fatty Acids and Fatty Acid–Sensing GPCRs GPR120: Obesity and Diabetes Oleoylethanolamide Biological Activities of Omega-3…
CHAPTER 5 Protein Structure and Function CHAPTER OUTLINE Primary Structure in Proteins Secondary Structure in Proteins The α-Helix β-Sheets Super-Secondary Structure Tertiary Structure of Proteins Forces Controlling Protein Structure Hydrogen Bonding…
CHAPTER 11 Carbohydrates: Fructose Metabolism and Feeding Behaviors CHAPTER OUTLINE Dietary Fructose Activation of Fructose Entry of Fructose into Glycolysis Fructose Consumption and Feeding Behaviors Metabolic Disruption With Fructose Consumption…
CHAPTER 12 Carbohydrates: Galactose Metabolism CHAPTER OUTLINE Dietary Galactose Entry of Galactose Into Glycolysis Disorders of Galactose Metabolism High-Yield Terms β-Galactosidase: intestinal enzyme complex involved in the hydrolysis of lactose…
Fig. 3.1 G-banded normal male karyotype illustrating the characteristic size, centromere position, and G-banding banding pattern for each human chromosome pair Chromosome Banding and Identification Launched in the early 1970s,…
Fig. 15.1 G-banded karyogram of a normal bone marrow cell Table 15.1 Glossary of cytogenetics terminology used in this chapter Acentric fragment A chromosome fragment lacking a centromere and therefore…
Tumor Chromosomal aberration(s) Gene(s) involved Clinical significance References Glial Pilocytic astrocytoma Gain of 5, 7/7q common, followed by 6, 8, 11, 12, 17, 19, 22 KIAA1549-BRAF from BRAF tandem duplication…
Fig. 9.1 Chromosome rearrangements can be produced by nonallelic homologous recombination between shared sequences or repeats of identical (direct repeats) or opposite (inverted repeats) orientation. Recombination between direct, nonallelic repeats…
Fig. 2.1 DNA structure. Schematic representation of a DNA double helix unwound to show the complementarity of bases and the antiparallel structure of the phosphate (P) and sugar (S) backbone…
Fig. 17.1 Schematic representation of the basic steps of the FISH procedure. Both the probe and chromosomal target are heat-denatured. Probe sequences hybridize to the complementary target sequences, and nonspecific…
