Cannabis: An Overview of the Empirical Literature
Introduction Marijuana (also referred to as cannabis) is a drug that is derived from the flowers, stems, leaves, and seeds of the hemp plant ( Cannabis sativa ). Cannabis is…
Animal Models of Substance Use Disorders: Motivational Perspective
Acknowledgments The author would like to thank Michael Arends for his assistance with manuscript preparation. Definitions Relevant to Animal Models Drug addiction, also known as substance use disorder, is a…
Cocaine
Key wordsCocaine use disorder, cocaine-induced anxiety disorder, cocaine-induced mood disorder, cocaine-induced psychotic disorder, cocaine-induced sexual dysfunction, cocaine-induced sleep disorder, craving and relapse, intoxication, intoxication delirium, withdrawal Introduction The effects…
Neuroinflammatory Processes in Drug Addiction
Acknowledgments We thank the National Institute on Alcohol Abuse and Alcoholism for its support through the Neurobiology of Adolescent Drinking in Adulthood (NADIA) consortium (AA020024, AA020023), the Bowles Center for…
Alcohol: Clinical Aspects
Acknowledgments We thank Catharine Helms and Robert H. Cormier, Jr., for their assistance with manuscript preparation. Introduction Alcohol is one of the oldest and the most widely used psychoactive substances…
Novel Methodologies : Proteomic Approaches in Substance Abuse Research
Acknowledgment The writing of this chapter was supported in part by funding of the following NIH grants: DA012498, DA003628, and DA06634 (SEH). Introduction The comprehensive sequencing of human and other…
Neurobehavioral Toxicology of Substances of Abuse
Ethanol (Alcohol) History Ethanol is surely the oldest known substance of abuse. The details of the original discovery of fermented beverages have been lost to time because of the unavailability…
Neurobiological Basis of Drug Reward and Reinforcement
Introduction Drug use disorders involve a number of factors including genetic and environmentally influenced predispositions, the actions of the drugs themselves, the immediate environment, and the neurobiological mechanisms that promote…
Metabolomics in Drug Response and Addiction
What Is Metabolomics? Metabolomics is the newest addition to the “omics” science. An “omics” has been defined as a neologism referring to a holistic view on biologic macromolecules, such as…
Neuroimaging Findings in Substance Use Disorders
Introduction A comprehensive understanding of the underlying neurobiology of alcohol and other drug use will likely prove essential in developing more effective prevention, early intervention, and treatment strategies. Ethical limitations…
