Cryptosporidium Laura Webb Lamps, MD Key Facts Etiology/Pathogenesis Cryptosporidium parvum causes diarrhea in healthy as well as immunocompromised children Transmitted by person-to-person contact or ingestion of contaminated food/water Clinical Issues…
Acute Rheumatic Fever Monica P. Revelo, MD, PhD Dylan V. Miller, MD Key Facts Terminology Acute, immunologically mediated, multisystemic inflammatory disease occurring a few weeks after an episode of pharyngeal…
Herpes Simplex Virus Esophagitis Laura Webb Lamps, MD Key Facts Etiology/Pathogenesis Esophagus most common site of infection HSV almost exclusively infects squamous epithelium Infection most often seen in immunocompromised patients…
Mitochondrial Myopathies Monica P. Revelo, MD, PhD Dylan V. Miller, MD Key Facts Terminology Heterogeneous group of maternally inherited diseases resulting from dysfunction in mitochondrial DNA-encoded gene products Microscopic Pathology…
Glycogen Storage Disease Monica P. Revelo, MD, PhD Key Facts Terminology Inherited autosomal recessive disorders due to deficiency in lysosomal enzymes resulting in glycogen accumulation that causes cellular dysfunction and…
Endocardial Fibroelastosis Monica P. Revelo, MD, PhD Key Facts Terminology Porcelain-like thickening of ventricular endocardium by layers of collagen and elastic fibers Etiology/Pathogenesis Endocardial fibroelastosis (EFE) should be regarded as…
Fatty Acid Metabolic Disorders Monica P. Revelo, MD, PhD Dylan V. Miller, MD Key Facts Terminology Inherited disorders due to defects in mitochondrial fatty-acid β-oxidation pathways; there are at least…
Interstitial Pulmonary Emphysema Larissa V. Furtado, MD Angelica R. Putnam, MD Key Facts Clinical Issues Most commonly occurs in premature infants with respiratory distress syndrome treated with assisted ventilated Interstitial…
Persistent Pulmonary Hypertension Larissa V. Furtado, MD Key Facts Terminology Persistent pulmonary hypertension of newborn (PPHN) Etiology/Pathogenesis Failure of pulmonary circulation to transition from a high- to low-pressure system at…
Aspiration Monica P. Revelo, MD, PhD Brandon T. Larsen, MD, PhD Key Facts Terminology Entry of particulate matter, fluid, or secretions from stomach, esophagus, oral cavity, nasal cavity, or oropharynx…
