Papillary Endothelial Hyperplasia Amitabh Srivastava, MD Key Facts Terminology Benign, reactive, intravascular papillary endothelial proliferation Clinical Issues Wide site distribution; located in deep dermis or subcutaneous tissue Macroscopic Features Small,…
Bacillary Angiomatosis David S. Cassarino, MD, PhD key Facts Terminology Reactive vascular proliferation associated with Bartonella (gram-negative coccobacilli) bacterial infection Etiology/Pathogenesis Most patients are immunocompromised, especially HIV/AIDS Also associated with…
Palisaded Myofibroblastoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign spindle cell tumor of modified smooth muscle cells in lymph node Clinical Issues Mainly inguinal region Mostly in males…
Deep Leiomyoma Cyril Fisher, MD, DSc, FRCPath Key Facts Clinical Issues Rare: 4% of benign soft tissue tumors Slow-growing mass Usually painless Deep subcutis or subfascial in limbs in either…
Sclerosing Pseudovascular Rhabdomyosarcoma David R. Lucas, MD Key Facts Terminology Variant of RMS characterized by extensive stromal fibrosis and pseudovascular, microalveolar, or cordlike architecture Clinical Issues Rare; only 34 reports…
Benign Metastasizing Leiomyoma Elizabeth A. Montgomery, MD Key Facts Terminology Rare lesion usually typified by multiple benignappearing smooth muscle neoplasms of lung in women with coexisting or past uterine leiomyoma…
Mammary-Type Myofibroblastoma Cyril Fisher, MD, DSc, FRCPath Key Facts Terminology Benign spindle cell lesion of modified smooth muscle cells in fibrous and fatty stroma Clinical Issues Identical to mammary myofibroblastoma…
Intravascular Leiomyomatosis Elizabeth A. Montgomery, MD Key Facts Terminology Rare condition featuring growth of nodules of benign smooth muscle in veins of myometrium, some with extension into extrauterine veins Clinical…
Leiomyomatosis Peritonealis Disseminata Cyril Fisher, MD, DSc, FRCPath Key Facts Etiology/Pathogenesis Associated with Pregnancy Hormonal therapy Hormone-secreting tumors Clinical Issues Females Fertile period Especially in 4th decade Throughout abdomen and…
Alveolar Rhabdomyosarcoma Khin Thway, BSc, MBBS, FRCPath Key Facts Terminology High-grade malignant round cell neoplasm showing partial differentiation towards skeletal muscle Etiology/Pathogenesis Characteristic PAX-FOXO1 balanced translocations in most t(2;13)(q35;q14) (majority)…
