Inflammatory Pseudotumor Key Facts Terminology Myofibroblastic tumor Etiology/Pathogenesis Some cases linked to HHV-8 Clonality demonstrated in some cases Clinical Issues Tumor more common in young individuals < 40 years old…
Lymphomatoid Granulomatosis Key Facts Terminology Angiocentric lymphoproliferative disorder composed of Epstein-Barr-infected B cells admixed with reactive T cells Clinical Issues Cough Dyspnea Microscopic Pathology Sheets of mixed, polymorphous atypical lymphoreticular…
Plasmacytoma Key Facts Clinical Issues Incidence Primary plasmacytomas of lung are rare May represent approximately 5% of all extramedullary plasmacytomas Tumor has been described essentially in adults Symptoms Cough Hemoptysis…
Atypical Adenomatous Hyperplasia Key Facts Terminology Microscopic proliferation of atypical alveolar lining cells measuring < 5 mm in greatest diameter Clinical Issues Incidental microscopic finding in lung tissues removed for…
Pulmonary BALT Lymphoma Key Facts Clinical Issues Most common presentation is solitary mass on routine imaging studies Most patients are asymptomatic Favorable prognosis; 5-year survival in approximately 85-95% Image Findings…
Bronchial Malignant Melanoma Key Facts Clinical Issues Incidence Approximately 0.01% of all lung neoplasms More common in adults in 6th decade of life Symptoms Cough Dyspnea Chest pain hemoptysis Fever…
IgG4 Sclerosing Lung Disease Key Facts Terminology Systemic disease of unknown etiology characterized by elevated production of IgG4(+) plasma cells and tissue stromal sclerosis Clinical Issues Slowly progressive disease with…
Neuroendocrine Carcinoma (Including Small Cell Carcinoma) Key Facts Terminology Spectrum of neoplasms ranging from low- to high-grade malignancy Clinical Issues Paraneoplastic syndromes Macroscopic Features Endobronchial or intraparenchymal tumor 0.5 to…
Pulmonary BALT Hyperplasia Key Facts Terminology Polyclonal proliferation of small lymphocytes arising within lung parenchyma Etiology/Pathogenesis Commonly associated with underlying autoimmune disorders such as Sjögren syndrome, rheumatoid arthritis, and collagen…
Mixed Tumor Key Facts Terminology Synonym: Pleomorphic adenoma (PA) Biphasic neoplasm with epithelial/myoepithelial and mesenchymal differentiation Clinical Issues Symptoms Cough Dyspnea Chest pain Hemoptysis Prognosis Excellent for benign tumors Malignant…
