Placental Transmogrification Key Facts Terminology Synonyms: Placentoid bullous lesion, giant bullous emphysema, pulmonary lipomatosis Benign unusual condition characterized by bizarre changes in shape of normal lung parenchyma Etiology/Pathogenesis Some cases…
Nonspecific Interstitial Pneumonia Key Facts Clinical Issues 25-60 years (average: 50 years) Diffuse, bilateral process, predominantly distributed in lower lobes Dyspnea Cough Fever Disease has insidious onset with slowly progressive…
Diffuse Alveolar Damage Key Facts Terminology Acute inflammatory reaction involving endothelial and epithelial cells of the alveolus Clinical Issues Nonspecific histologic pattern of acute lung injury that may occur in…
Rosai-Dorfman Disease Key Facts Terminology Synonym: Sinus histiocytosis with massive lymphadenopathy (SHML) Etiology/Pathogenesis Unknown Possible infectious origin Possible immunologic response Clinical Issues R-D disease is unusual tumoral condition more commonly…
Hyalinizing Granuloma Key Facts Etiology/Pathogenesis Unusual condition of unknown origin May have autoimmune origin PHG may be associated with conditions with similar histological features, including Retroperitoneal fibrosis Sclerosing mediastinitis Clinical…
Diffuse Large Cell Lymphoma Key Facts Etiology/Pathogenesis May arise from progressive transformation of preexisting low-grade MALT lymphoma Clinical Issues Adults from 50-70 years of age Usually peripheral in location Microscopic…
Benign Metastasizing Leiomyoma Key Facts Clinical Issues 30-50 years of age Exclusively observed in women Lesions are usually multiple and may be bilateral, suggesting metastatic disease Macroscopic Features Well-circumscribed, tan-white…
Ganglioneuroblastoma Key Facts Terminology P-GNB Clinical Issues Incidence GNBs are exceedingly rare tumors in the lung Cases described have been in adult patients There is no gender predilection Symptoms Cough…
Juvenile Xanthogranuloma Key Facts Terminology Abbreviation: Pulmonary juvenile xanthogranuloma (JXG) Definition Non-Langerhans histiocytic lesion Etiology/Pathogenesis Contrary to other histiocytic lesions, cell of origin for JXG is unknown Plasmacytoid monocyte has…
Angiolymphoid Hyperplasia with Eosinophilia Key Facts Terminology Angiolymphoid hyperplasia with eosinophilia (ALHE) Epithelioid hemangioma Clinical Issues Presentation Cough Dyspnea Asthma Treatment of choice: Complete surgical resection Lobectomy Wedge resection Prognosis:…
