Cutaneous Reactions to Retinoids

Nov 20, 2016 by in PHARMACY Comments Off on Cutaneous Reactions to Retinoids

Fig. 34.1 Severe dryness and fissuring of lips and nose in a patient on isotretinoin Fig. 34.2 Xerotic skin with reticulate fissuring seen in asteatotic dermatitis over the ankle in…

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Drug-Induced Photosensitivity

Nov 20, 2016 by in PHARMACY Comments Off on Drug-Induced Photosensitivity

  Phototoxicity Photoallergy Incidence High Low Amount of agent required for photosensitivity Large Small Onset after exposure to photosensitizer and light Minutes to hours 24 h or more Occurs after…

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Acne and Drug Reactions

Nov 20, 2016 by in PHARMACY Comments Off on Acne and Drug Reactions

Fig. 15.1 Primary lesions Secondary Lesions Comedones and cysts can arise secondary to inflammatory papules and pustules but are often not present. Pits and scars are evident in severe cases….

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Drug Eruptions and Erythroderma

Nov 20, 2016 by in PHARMACY Comments Off on Drug Eruptions and Erythroderma

Diseases commonly associated with or preceding erythroderma a Dermatologic diseases Psoriasis Atopic dermatitis Pityriasis rubra pilaris Contact and other types of dermatitis Dermatophytosis Ichthyosis Pemphigus foliaceus Systemic diseases Lymphoma: CTCL,…

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Pigment Changes and Drug Reactions

Nov 20, 2016 by in PHARMACY Comments Off on Pigment Changes and Drug Reactions

Most potent phenol and catechol derivatives Non-phenolic/catecholic agents Hydroquinone Mercury Monobenzyl ether of hydroquinone Arsenic p-tert-Butylchatechol Cinnamic aldehyde p-tert-Butylphenol p-phenylenediamine (PPD) p-tert-Amylphenol Benzyl alcohol – Azelaic acid – Corticosteroids –…

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Morbilliform Drug Eruptions

Nov 20, 2016 by in PHARMACY Comments Off on Morbilliform Drug Eruptions

Fig. 5.1 A typical morbilliform drug eruption, with pink erythematous papules coalescing into larger plaques Fig. 5.2 Morbilliform drug eruption in an adult patient with pink erythematous papules coalescing into…

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Drug-Induced Alopecia

Nov 20, 2016 by in PHARMACY Comments Off on Drug-Induced Alopecia

Drug-induced alopecia Idiopathic alopecia Temporal association of drug initiation and alopecia No association with initiation of drug Cessation of drug leads to recovery and restoration of hairs and reversion of…

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Lymphoma and Pseudolymphoma and Drug Reactions

Nov 20, 2016 by in PHARMACY Comments Off on Lymphoma and Pseudolymphoma and Drug Reactions

Fig. 19.1 This is true cutaneous lymphoma—erythematous papules in the groin. Clinical clues it is a true lymphoma are that the lesions are multiple, chronic, and on non-sun-exposed skin. The…

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