Small Molecule Agonists and Antagonists of TRPV4

Nov 18, 2017 by in PHARMACY Comments Off on Small Molecule Agonists and Antagonists of TRPV4

Chapter 12 Small Molecule Agonists and Antagonists of TRPV4 Matthew A.J. Duncton*    Renovis, Inc. (a wholly owned subsidiary of Evotec AG), South San Francisco, California, USA* Corresponding author: mattduncton@yahoo.com Abstract Transient…

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TRPM8 as a Target for Analgesia

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Chapter 14 TRPM8 as a Target for Analgesia Rory Mitchell1,*; Susan Fleetwood-Walker1,*    1 Centre for Integrative Physiology, School of Biomedical Sciences, College of Medicine & Veterinary Medicine, University of Edinburgh, Scotland,…

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TRPV1 Agonist Cytotoxicity for Chronic Pain Relief: From Mechanistic Understanding to Clinical Application

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Chapter 6 TRPV1 Agonist Cytotoxicity for Chronic Pain Relief From Mechanistic Understanding to Clinical Application Dorothy Cimino Brown1,2,*; Michael J. Iadarola3    1 Veterinary Clinical Investigations Center, School of Veterinary Medicine, University…

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TRP Gene Polymorphism and Disease Risk

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Chapter 4 TRP Gene Polymorphism and Disease Risk Ina Kraus-Stojanowic1; Ralf Baron2; Ingolf Cascorbi1,*    1 Institute of Experimental and Clinical Pharmacology, University Hospital Schleswig-Holstein, Kiel, Germany2 Division of Neurological Pain Research…

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TRPML1-Dependent Processes as Therapeutic Targets

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Chapter 25 TRPML1-Dependent Processes as Therapeutic Targets Kartik Venkatachalam1,*; Kirill Kiselyov2,*    1 Department of Integrative Biology and Pharmacology, University of Texas School of Medicine, Houston, TX, USA2 Department of Biological Sciences,…

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TRPs in Respiratory Disorders: Opportunities Beyond TRPA1

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Chapter 26 TRPs in Respiratory Disorders Opportunities Beyond TRPA1 Alexander Zholos1,*; Lorcan McGarvey2; Madeleine Ennis2    1 Department of Biophysics, Educational and Scientific Centre “Institute of Biology”, Taras Shevchenko Kiev National University,…

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