Chapter 8 Clinical and Preclinical Experience with TRPV1 Antagonists as Potential Analgesic Agents Arthur Gomtsyan1,*; Jill-Desiree Brederson2 1 Department of Chemistry, Research and Development, AbbVie Inc., North Chicago, Illinois, USA2 Global…
Chapter 21 Targeting of Transient Receptor Potential Channels in Digestive Disease Daniel P. Poole1,2,*; TinaMarie Lieu1; Nicholas A. Veldhuis1,3; Pradeep Rajasekhar1; Nigel W. Bunnett1,4 1 Monash Institute of Pharmaceutical Sciences, Parkville,…
Chapter 25 TRPML1-Dependent Processes as Therapeutic Targets Kartik Venkatachalam1,*; Kirill Kiselyov2,* 1 Department of Integrative Biology and Pharmacology, University of Texas School of Medicine, Houston, TX, USA2 Department of Biological Sciences,…
Chapter 26 TRPs in Respiratory Disorders Opportunities Beyond TRPA1 Alexander Zholos1,*; Lorcan McGarvey2; Madeleine Ennis2 1 Department of Biophysics, Educational and Scientific Centre “Institute of Biology”, Taras Shevchenko Kiev National University,…
Chapter 18 Transient Receptor Potential Channels in Hypertension and Metabolic Syndrome Zhiming Zhu*; Daoyan Liu; Shiqiang Xiong Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Third…
Chapter 23 Are Brain TRPs Viable Targets for Curing Neurodegenerative Disorders and Improving Mental Health? Bernd Nilius1; Arpad Szallasi2,* 1 Katholieke Universiteit of Leuven, Department of Cellular and Molecular Medicine, Laboratory…
Chapter 20 TRP Channels in Cardiovascular Disease Kavisha Singh; Nancy Luo; Paul Rosenberg* Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA* Corresponding author: rosen029@mc.duke.edu…
Chapter 11 Is TRPV3 a Drug Target?—A Decade of Learning Neelima Khairatkar Joshi* Glenmark Research Centre, Navi Mumbai, Glenmark Pharmaceuticals Ltd, India* Corresponding author: neelima_joshi@glenmarkpharma.com Abstract Transient receptor potential cation channel,…
Chapter 27 Conclusions Magdalene Moran* Hydra Biosciences Cambridge, MA, USA* Corresponding author: mmoran@hydrabiosciences.com Keywords TRP Cation Channel Drug discovery As you have read, it is a very exciting time for transient…
Chapter 15 Connecting TRP Channels and Cerebrovascular Diseases Anil Zechariah1,2,3; Donald G. Welsh1,2,3,* 1 Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada2 Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta,…
