Fig. 5.1 Potential for TRPV1 modulation to reduce pain related to opioid-induced hyperalgesia. Either capsaicin-based defunctionalization or outright TRPV1 antagonism may be useful in alleviating this subset of chronic pain Further…
Chapter 14 Amino Acid Metabolism Margaret E. Brosnan, PhD and John T. Brosnan, DPhil, DSc∗ This discussion of amino acid metabolism focuses on the metabolism of the 20 α-amino (or…
Chapter 16 Metabolism of Fatty Acids, Acylglycerols, and Sphingolipids Hei Sook Sul, PhD Common Abbreviations ACP acyl carrier protein AMPK 5′-AMP–activated protein kinase cAMP 3′-5′-cyclic adenosine monophosphate CoA coenzyme A…
Chapter 12 Carbohydrate Metabolism Synthesis and Oxidation Mary M. McGrane, PhD Common Abbreviations AMPK adenosine monophosphate (AMP)-activated protein kinase ChREBP carbohydrate response element binding protein CoA coenzyme A F2,6P2 fructose…
Chapter 21 Cellular and Whole-Animal Energetics Darlene E. Berryman, PhD, RD and Matthew W. Hulver, PhD Common Abbreviations ADP adenosine 5’-diphosphate ATP adenosine 5’-triphosphate BEE basal energy expenditure (also known…
Chapter 6 Structure, Nomenclature, and Properties of Lipids J. Thomas Brenna, PhD and Gavin L. Sacks, PhD Common Abbreviations CMC critical micellar concentration FFA free fatty acids LT leukotrienes LX…
Chapter 24 Niacin, Riboflavin, and Thiamin W. Todd Penberthy, PhD∗ Common Abbreviations FAD flavin adenine dinucleotide FMN flavin mononucleotide NAD nicotinamide adenine dinucleotide NADP nicotinamide adenine dinucleotide phosphate NaMN nicotinate…
Chapter 18 Lipid Metabolism Polyunsaturated Fatty Acids Sarah K. Orr, BSc, Chuck T. Chen, BSc, Arthur A. Spector, MD and Richard P. Bazinet, PhD Common Abbreviations ARA arachidonic acid DHA…
Chapter 19 Regulation of Fuel Utilization in Response to Food Intake Martha H. Stipanuk, PhD Common Abbreviations AMPK 5′-AMP-activated protein kinase cAMP 5′-cyclic AMP CoA coenzyme A FoxO forkhead box…
Chapter 15 Protein and Amino Acid Requirements Crystal L. Levesque, PhD and Ronald O. Ball, PhD∗ Common Abbreviations BV biological value DAAO direct amino acid oxidation IAAO indicator amino acid…
