Ethics in Laboratory Research
Nonmaleficence Do not harm yourself or other people Beneficence Help yourself and other people Autonomy Allow rational individuals to make free, informed choices Justice Treat people fairly; treat equals equally,…
Getting Your IACUC Proposal Approved
Breeding Blood/tissue collection Death as an endpoint Behavioral studies Administration of experimental agents Major survival surgery Antibody production/collection (monoclonal) using the ascites method Use of hazardous agents Multiple major survivor…
Use of Genetically Engineered Mice for Research
Melina R. Kibbe and Scott A. LeMaire (eds.)Success in Academic SurgerySuccess in Academic Surgery: Basic Science201410.1007/978-1-4471-4736-7_12© Springer-Verlag London 2014 12. Use of Genetically Engineered Mice for Research Kerry-Ann McDonald1 and Allan Tsung2 (1) Department of Surgery, University…
Choosing a Good Basic Science or Translational Research Mentor
Curious Principle Number One Everyone wants a mentor Curious Principle Number Two Everyone enjoys talking about their mentor (sometimes more than other people like listening to them talking about their…
Modern Techniques for DNA and RNA Assessments
Fig. 8.1 RT-PCR. Following RNA purification and construction of tagged cDNAs, PCR amplification is done with quantitative results available in real time. PCR cycles required to shift from an initial…
How to Set Up, Staff, and Fund Your Basic Science or Translational Research Laboratory
Intramural Extramural Start-up from your own institution Personal donations and philanthropy Pilot grant funding (departmental or institutional) Disease-oriented foundations Regional Veterans Integrated Service Network (VISN) pilot funding Department of Veterans…
The Cardiovascular System
Chapter 10 The Cardiovascular Exam Salvatore Mangione, MD “Just when the lamps were lit, a messenger came and brought me to the Emperor as he had bidden. Three doctors had…
Heart Murmurs
Chapter 12 Heart Murmurs Salvatore Mangione, MD “That the stethoscope will come in general use notwithstanding its value I am extremely doubtful, because its beneficial application requires much time and…
General Appearance, Facies, and Body Habitus
Chapter 1 General Appearance, Facies, and Body Habitus Salvatore Mangione, MD “I knew you came from Afghanistan. From long habit, the train of thought ran so swiftly through my mind…
