A Primer on Immunostains
(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA KeywordsCytokeratinMelanomaCarcinomaSarcomaLymphomaMesotheliomaGerm cell tumorVascularNeuralMyoepithelial The use of immunostains is a highly complex field in and of itself and…
Neuroendocrine Neoplasms
Location Neuroendocrine cell type (secreted product) Corresponding neoplasm Cytokeratin expression Intestine and appendix EC cell (serotonin); D, L cells; others WD-NET Positive Gastric fundus ECL cell (histamine) WD-NET Positive Gastric…
So You Want to Get a Job
(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA KeywordsMedicarePart APart BBillingInterviewPrivate practice Congratulations! You’ve survived residency and you are looking for a job. If you…
Using the Microscope
(1) Department of Pathology, Sinai Hospital of Baltimore Pathology, Baltimore, MD, USA KeywordsMicroscopeErgonomicsKöhlerParfocalCondenserObjectiveEyeglasses Using the Microscope Upon arriving in the pathology department, you will most likely be given a…
Tumors of Uncertain Differentiation
(1) Department of Pathology, University of Manitoba Max Rady College of Medicine, Winnipeg, MB, Canada KeywordsAlveolar soft part sarcomaDesmoplastic small round cell tumorEpithelioid sarcomaEwing SarcomaExtrarenal rhabdoid tumorExtraskeletal myxoid chondrosarcomaHemosiderotic…
Fibroblastic/Myofibroblastic Tumors
(1) Department of Pathology, University of Manitoba Max Rady College of Medicine, Winnipeg, MB, Canada KeywordsDeep (desmoid-type) fibromatosisDermatofibrosarcoma protuberansElastofibromaGardner-associated fibromaInflammatory myofibroblastic tumorNodular fasciitisNuchal-type fibromaSolitary fibrous tumorSuperficial fibromatosis Fibroblastic and…
Histologic Examination and Ancillary Studies in Soft Tissue Pathology
(1) Department of Pathology, University of Manitoba Max Rady College of Medicine, Winnipeg, MB, Canada KeywordsChromosomal karyotypingEpithelioid tumorsImmunohistochemical stainMyxoid tumorsPleomorphic tumorsReverse-transcriptase polymerase chain reaction (RT-PCR)Round cell tumorsSpindled cell pattern…
Neural and Nerve Sheath Lesions
(1) Department of Pathology, University of Manitoba Max Rady College of Medicine, Winnipeg, MB, Canada KeywordsGranular cell tumorMalignant peripheral nerve sheath tumorNeurofibromaPerineuriomaPeripheral nerveSchwannoma Peripheral nerves are composed of axons…
Skeletal Muscle Tumors
(1) Department of Pathology, University of Manitoba Max Rady College of Medicine, Winnipeg, MB, Canada KeywordsAlveolar rhabdomyosarcomaEmbryonal rhabdomyosarcomaPleomorphic rhabdomyosarcomaRhabdomyomaSkeletal muscle tumor Histologically, skeletal muscle cells are distinguished by eosinophilic…