Basicmedical Key

Figure 52.1 Maturation of blood cells. With the exception of platelets and erythrocytes, all of the mature blood cells shown participate in immune responses. However, only cells of lymphoid origin (cytolytic T…

Figure 61.1 Pharmacologic management of allergic rhinitis. INS, intranasal steroids. (From American Academy of Otolaryngology. Clinical practice guideline: allergic rhinitis. 2015. http://www.entnet.org/content/clinical-practice-guideline-allergic-rhinitis.) Intranasal Glucocorticoids The basic pharmacology of the glucocorticoids is discussed in…

Figure 40.1 Relationship of ventricular diameter to contractile force. In the normal heart and the failing heart, increased fiber length produces increased contractile force. However, for any given fiber length, contractile force…

Black Box Warning: Methadone Methadone can cause life-threatening QT prolongation as well as severe respiratory depression. Because of the long half-life of methadone, it should only be prescribed by health…

Figure 72.1 Mechanism of action of aminoglycosides. A, Protein synthesis begins with binding of the 50S and 30S ribosomal subunits to messenger RNA (mRNA), followed by attachment of the first amino acid…

Figure 13.1 Structures of representative catecholamines and noncatecholamines. Catecholamines: All of the catecholamines share the same basic chemical formula. Because of their biochemical properties, the catecholamines cannot be used orally, cannot cross…

Figure 86.1 Anatomy of the ear. The purple arrows indicate flow of the mucociliary system, which can transport bacteria out of the middle ear.  Otitis Media and Its Management Otitis media (OM),…

50–400 mg every 2–4 wkTransdermal patchTestosteroneAndrodermOne patch/day (delivers 2 or 4 mg/24 hr)IIIApplied to the arm, back, abdomen, or thigh, but not the scrotum. Causes local irritation.Transdermal gelTestosteroneAndroGel, Testim5–10 g…

to adult dose PolycarbophilFiberCon, othersTablets Adults: 1250 mg 1–4 times a day Children 6–12 yr: 625 mg 1–4 times a daySURFACTANTDocusate sodiumColace, othersCapsules, tablets, syrup, liquid Adults and children older…

Mild Aspirin or aspirin combinations Triptans Moderate Dihydroergotamine (DHE) Ergotamine NSAID combination products Severe Metoclopramide Triptans Ergotamine or DHE NSAIDs (Ketorolac) Prophylaxis Beta blockers Tricyclic antidepressants Antiepileptics Consider hormonally related…