– Immunology
Helper T cells (CD4) • Release IL-2, which mainly causes maturation of cytotoxic T cells • Release IL-4, which mainly causes B-cell maturation into plasma cells • Involved in delayed-type hypersensitivity (brings in…
– Wound Healing
Inflammation (days 1–10) – PMNs, macrophages; epithelialization (1–2 mm/day) Proliferation (5 days–3 weeks) – fibroblasts, collagen deposition, neovascularization, granulation tissue formation; type III collagen replaced with type I Remodeling (3…
– Pituitary
Hypothalamus – releases TRH, CRH, GnRH, GHRH, and dopamine into median eminence; passes through neurohypophysis on way to adenohypophysis Dopamine – inhibits prolactin secretion Posterior pituitary (neurohypophysis) • ADH – supraoptic…
4: The nature and scale of error and harm
Studying errors and adverse events There are a number of methods of studying errors and adverse events, each of which has evolved over time and been adapted to different contexts….
18: Teams create safety
What is a team? A team in a formal sense is a group of individuals with a shared, common goal who, while they each have defined individual tasks, achieve their…
19: Safe organizations: bringing it all together
Clinical microsystems A clinical microsystem is a group of clinicians and staff working together with a shared clinical purpose to provide care for a defined population of patients (Mohr, Batalden…
8: Understanding how things go wrong
(TOFT, 2001) Following an Internal Enquiry at QMC, Professor Brian Toft was commissioned by the Chief Medical Officer of England to conduct an enquiry into the death and to advise…
