Pharmacology of Parasitic Infections Louise C. Ivers and Edward T. Ryan INTRODUCTION MALARIAL PLASMODIA & CASES 1–2 Physiology of Malarial Plasmodia Life Cycle Heme Metabolism Electron Transport Chain Pharmacology of…
Pharmacology of Bone Mineral Homeostasis David M. Slovik and Ehrin J. Armstrong INTRODUCTION & CASE PHYSIOLOGY OF BONE MINERAL HOMEOSTASIS Structure of Bone Mineral Balance Regulation of Bone Remodeling Hormonal…
Principles of Cellular Excitability and Electrochemical Transmission Elizabeth Mayne, Lauren K. Buhl, and Gary R. Strichartz INTRODUCTION & CASE CELLULAR EXCITABILITY Ohm’s Law Ion Channels Channel Selectivity, the Nernst Equation,…
Pharmacology of Cancer: Signal Transduction David A. Barbie and David A. Frank INTRODUCTION & CASE BIOCHEMISTRY OF INTERCELLULAR AND INTRACELLULAR SIGNAL TRANSDUCTION Growth Factors and Growth Factor Receptors Intracellular Signal…
Pharmacology of Immunosuppression Elizabeth A. Brezinski, Lloyd B. Klickstein, and April W. Armstrong INTRODUCTION & CASE PATHOPHYSIOLOGY Transplantation Solid Organ Rejection Graft-Versus-Host Disease (GVHD) Autoimmunity PHARMACOLOGIC CLASSES AND AGENTS Inhibitors…
INTRODUCTION Cholinergic pharmacology is centered on the properties of the first identified neurotransmitter, acetylcholine (ACh). The functions of cholinergic pathways are diverse; generally, they involve the neuromuscular junction (NMJ), the…
Pharmacology of Cholesterol and Lipoprotein Metabolism Tibor I. Krisko, Ehrin J. Armstrong, and David E. Cohen INTRODUCTION & CASE BIOCHEMISTRY AND PHYSIOLOGY OF CHOLESTEROL AND LIPOPROTEIN METABOLISM Metabolism of ApoB-Containing…
Pharmacology of Bacterial Infections: DNA Replication, Transcription, and Translation Alexander J. McAdam and Donald M. Coen INTRODUCTION & CASE BIOCHEMISTRY OF BACTERIAL DNA REPLICATION, TRANSCRIPTION, AND TRANSLATION DNA Structure DNA…
INTRODUCTION While the heart provides cardiac output, the blood vessels play a critical role in the distribution of oxygen and nutrients to metabolically active tissues. Blood flow to these tissues…
Pharmacology of GABAergic and Glutamatergic Neurotransmission Stuart A. Forman, Hua-Jun Feng, Janet Chou, Jianren Mao, and Eng H. Lo INTRODUCTION & CASE OVERVIEW OF GABAERGIC AND GLUTAMATERGIC NEUROTRANSMISSION PHYSIOLOGY OF…
