Clinical Drug Evaluation and Regulatory Approval
FDA Review FDA Approval Approval in Other Countries Expanded Access of an Investigational Drug or an Approved Drug with Restricted Distribution Drug Labeling Drug Naming Additional Indications REGULATORY ASPECTS OF…
General Anesthetic Pharmacology
INTRODUCTION Before the discovery of general anesthetics, pain and shock severely limited the possibilities for surgical intervention. Postoperative mortality dropped dramatically following the first public demonstration of diethyl ether at…
Pharmacokinetics
INTRODUCTION Even the most promising of pharmacologic therapies will fail in clinical trials if the drug is unable to reach its target organ at a concentration sufficient to have a…
Pharmacology of Cancer: Genome Synthesis, Stability, and Maintenance
INTRODUCTION Cancer therapy has traditionally been based on the principle that tumor cells are traversing the cell cycle frequently and are thus more sensitive than normal cells to interference with…
