Protocol for the Examination of Thyroid Gland Specimens
Protocol for the Examination of Thyroid Gland Specimens Lester D. R. Thompson, MD Examination of Thyroid Gland Carcinoma Specimens Resection Procedure _ _ _Thyroid lobectomy _ _ _Right _ _…
Squamous Cell Carcinoma
Squamous Cell Carcinoma Lester D. R. Thompson, MD Key Facts Terminology Thyroid primary squamous cell carcinoma is composed entirely of squamous cells without mucocytes and without direct invasion from adjacent…
Antibody Index
Antibody Index Antibodies Discussed Antibody Name/Symbol Antibody Description Clones/Alternative Names α-1-antichromotrypsin alpha 1 antichromotrypsin A1ACT α-1-antitrypsin alpha 1 antitrypsin A1AT α-amylase alpha amylase A-amylase α-fetoprotein alpha 1 fetoprotein AFP, Z5A06,…
Undifferentiated (Anaplastic) Carcinoma
Undifferentiated (Anaplastic) Carcinoma Lester D. R. Thompson, MD Key Facts Terminology Highly aggressive malignancy of undifferentiated cells Etiology/Pathogenesis Preexisting benign or malignant thyroid disease in nearly all cases, with transformation…
Follicular Cell-Derived Lesions in Ectopic Locations (Struma Ovarii)
Follicular Cell-Derived Lesions in Ectopic Locations (Struma Ovarii) Bruce M. Wenig, MD Key Facts Terminology Struma ovarii Ovarian teratomas in which thyroid tissue is predominant (at least 50%) or sole…
Riedel Thyroiditis
Riedel Thyroiditis Bruce M. Wenig, MD Key Facts Terminology Idiopathic fibrosing process and not per se an inflammatory (thyroiditis) thyroid disease Etiology/Pathogenesis Association between RT and Hashimoto thyroiditis supports autoimmune…
Subacute Granulomatous Thyroiditis (de Quervain)
Subacute Granulomatous Thyroiditis (de Quervain) Lester D. R. Thompson, MD Key Facts Terminology Self-limited inflammatory condition characterized by epithelioid histiocytes, multinucleated giant cells, and acute inflammatory cells Clinical Issues Female…
Dyshormonogenetic Goiter
Dyshormonogenetic Goiter Lester D. R. Thompson, MD Key Facts Terminology Thyroid enlargement due to hereditary defect in thyroid hormone synthesis Clinical Issues Usually autosomal recessive, enzyme defect in one of…
Solid Cell Nest
Solid Cell Nest Lester D. R. Thompson, MD Key Facts Terminology Small remnant of ultimobranchial apparatus, associated with development of thyroid C-cells Clinical Issues Posteromedial and lateral area of bilateral…
Lymphangioma
Lymphangioma Brenda L. Nelson, DDS, MS Lester D. R. Thompson, MD Key Facts Terminology Cystic hygroma Malformation of lymphatic system, generally considered congenital Etiology/Pathogenesis Associated with chromosomal abnormalities Clinical Issues…
