Post-Chemotherapy Histiocyte-rich Pseudotumor of Spleen Roberto N. Miranda, MD Key Facts Terminology Residual splenic mass after chemotherapy composed of viable nonneoplastic cells and necrotic neoplastic cells Etiology/Pathogenesis Chemotherapy is toxic…
Lymphomatoid Granulomatosis Francisco Vega, MD, PhD Key Facts Terminology Extranodal angiocentric &/or angiodestructive EBV(+) B-cell lymphoproliferative disorder Clinical Issues Most frequent in young adults (˜ 30-40 years) Lung is most…
Mycosis Fungoides Sa A. Wang, MD Key Facts Terminology Primary cutaneous T-cell lymphoma characterized by Epidermotropism Clinical course showing stepwise evolution of patches, plaques, and tumors Clinical Issues Overall indolent…
Autoimmune Lymphoproliferative Syndrome Sa A. Wang, MD Key Facts Etiology/Pathogenesis Disease of disrupted lymphocyte homeostasis as result of defective Fas-mediated apoptosis Many mutations have been identified in ALPS Type I:…
Classical Hodgkin Lymphoma Francisco Vega, MD, PhD Key Facts Clinical Issues CHL can involve extranodal tissues Most common: Spleen, lungs, liver, and bone marrow Macroscopic Features Variable patterns of splenic…
Adult T-cell Leukemia/Lymphoma, HTLV-1+ Carlos E. Bueso-Ramos, MD, PhD Roberto N. Miranda, MD Key Facts Terminology Peripheral T-cell leukemia/lymphoma caused by human T-cell lymphotropic virus type 1 (HTLV-1) 4 clinical…
Nodular Lymphocyte Predominant Hodgkin Lymphoma Pei Lin, MD Key Facts Clinical Issues Peak incidence in 4th decade, affects all age groups Patients often present with stage I or II nodal…
Nodular Sclerosis Hodgkin Lymphoma C. Cameron Yin, MD, PhD Key Facts Terminology Nodular sclerosis is type of CHL composed of lacunar-type HRS cells and inflammatory cells forming nodules surrounded by…
Myeloid/Monocytic Sarcoma Carlos E. Bueso-Ramos, MD, PhD Key Facts Clinical Issues Myeloid/monocytic sarcoma (MS) is tumor mass Can develop de novo (27%), concurrently with, or after diagnosis of AML Can…
Extranodal Marginal Zone B-cell Lymphoma (MALT Lymphoma) Pei Lin, MD Key Facts Etiology/Pathogenesis Infectious agents are implicated in pathogenesis of MALT lymphomas at specific sites Helicobacter pylori: Stomach Campylobacter jejuni:…
