Pharmacokinetics
Chapter 1 Pharmacokinetics I. General (Fig. 1-1) A. Pharmacokinetics is the fate of drugs within the body. B. It involves drug: 1. Absorption 2. Distribution 3. Metabolism 4. Excretion 1-1…
Drugs Used in the Treatment of Hypothalamic, Pituitary, Thyroid, and Adrenal Disorders
Chapter 23 Drugs Used in the Treatment of Hypothalamic, Pituitary, Thyroid, and Adrenal Disorders I. General Considerations A. Overview 1. A hormone is a substance secreted by one tissue or…
Pharmacodynamics
Chapter 2 Pharmacodynamics I. Definitions A. Pharmacodynamics • Involves the biochemical and physiologic effects of drugs on the body. B. Receptor • A macromolecule to which a drug binds to…
Antimicrobial Drugs
Chapter 27 Antimicrobial Drugs I. General Considerations A. Keys to successful antimicrobial therapy 1. Selective toxicity • Destroy pathogenic microorganisms with minimal adverse effects to host Antimicrobial therapy is an…
Drugs Used in the Treatment of Gastrointestinal Disorders
Chapter 21 Drugs Used in the Treatment of Gastrointestinal Disorders I. Peptic Disorders A. Pathology; diseases include 1. Ulcers of the stomach, esophagus, and duodenum Helicobacter pylori often responsible for…
Drugs Used in the Treatment of Coagulation Disorders
Chapter 16 Drugs Used in the Treatment of Coagulation Disorders I. General Considerations A. Clot formation at the tissue level results from complex interactions (Fig. 16-1). 1. Enzymatic pathway for…
Other Anti-Infective Drugs
Chapter 28 Other Anti-Infective Drugs I. Antimycobacterial Drugs (Box 28-1) • The management of tuberculosis is summarized in Table 28-1. BOX 28-1 Antimycobacterial Drugs Dapsone (leprosy) Ethambutol Isoniazid Pyrazinamide Rifabutin…
Other Cardiovascular Drugs
Chapter 14 Other Cardiovascular Drugs I. General Considerations A. Goal of antianginal therapy • Decrease oxygen demand of myocardial tissue or increase oxygen supply (Fig. 14-1). 14-1 Effects of nitrates,…
Antiarrhythmic Drugs
Chapter 12 Antiarrhythmic Drugs I. General Considerations A. Cardiac contraction (Fig. 12-1): five-step process 1. Spontaneous development of the action potential in the sinoatrial (SA) node 2. Spread of the…
