Smooth Muscle Preparations

Jul 24, 2016 by in PHARMACY Comments Off on Smooth Muscle Preparations

The results in Figure 4.1 can be displayed graphically by plotting the log concentration versus response (Figure 4.2). Figure 4.2 Log concentration–response curves for cholinesters. Questions 1. The responses are…

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Basic Pharmacological Principles

Jul 24, 2016 by in PHARMACY Comments Off on Basic Pharmacological Principles

According to the Law of Mass Action, the value of the dissociation constant (Kd) could be derived as follows: (2.2) It was fully appreciated at the time that Kd is…

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Isolated Cells

Jul 24, 2016 by in PHARMACY Comments Off on Isolated Cells

To count the number of live cells in a suspension, the following procedure is followed: The haemocytometer is cleaned with alcohol and dried using tissue paper and lens tissue. The…

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Biochemical Pharmacology

Jul 24, 2016 by in PHARMACY Comments Off on Biochemical Pharmacology

where the molar extinction coefficient of TNB is 1.36 × 104 L/mol/cm. This is the absorbance of a 1 M solution in a 1 cm light path. The total volume…

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Isolated Tissues and Organs

Jul 24, 2016 by in PHARMACY Comments Off on Isolated Tissues and Organs

Two designs of transducer are used, (1) isotonic, involving changes in length of the muscle and (2) isometric, where the length of the tissue is kept constant by an opposing…

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Skeletal Muscle

Jul 24, 2016 by in PHARMACY Comments Off on Skeletal Muscle

Figure 6.2 Chart® record of antagonism of acetylcholine by d-tubocurarine in the presence of 1 μM serine in leech isolated dorsal muscle. The bath volume was 25 mL, and the…

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Cardiovascular Preparations

Jul 24, 2016 by in PHARMACY Comments Off on Cardiovascular Preparations

It should be seen that salbutamol is about 100 times less potent than isoprenaline, suggesting that both drugs were acting on β1-adrenoceptors in the heart. At the doses selected, neither…

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Communicating Results

Jul 24, 2016 by in PHARMACY Comments Off on Communicating Results

html xmlns=”http://www.w3.org/1999/xhtml”> 10 Communicating Results All the time, effort and expense invested in performing an experiment is lost if the results and conclusions are not communicated to supervisors, peers and…

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