Pituitary and hypothalamic hormones

Jun 21, 2016 by in PHARMACY Comments Off on Pituitary and hypothalamic hormones

Fig. 43.1 Control mechanisms for the release of growth hormone, gonadotropins and prolactin from the anterior pituitary.For control of other hormones, see Ch. 41 (thyroid) and Ch. 44 (adrenocorticotropic hormones)….

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Ischaemic heart disease

Jun 21, 2016 by in PHARMACY Comments Off on Ischaemic heart disease

Fig. 5.1 Aspects of inflammatory processes that contribute to coronary heart disease.Multifactorial processes contribute to coronary heart disease; endothelium is damaged and activated; platelets adhere and promote leucocyte infiltration and…

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Systemic and pulmonary hypertension

Jun 21, 2016 by in PHARMACY Comments Off on Systemic and pulmonary hypertension

Blood pressure is maintained within fairly narrow limits due to modulation by a series of physiological reflexes that are triggered by both acute and chronic changes in blood pressure. There…

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Female reproduction

Jun 21, 2016 by in PHARMACY Comments Off on Female reproduction

Fig. 45.1 Endocrine control of the menstrual cycle. FSH drives the developing ovarian follicle to convert androgens produced by its thecal cells into oestradiol (Fig. 44.2) within its granulosa cells….

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Haemostasis

Jun 21, 2016 by in PHARMACY Comments Off on Haemostasis

Fig. 11.1 Platelets and platelet aggregation.Subendothelial macromolecules such as von Willebrand factor and collagen interact with glycoprotein receptors (GPVI and GPIb) on platelets, causing activation of platelets and upregulation of…

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Drug therapy in special situations

Jun 21, 2016 by in PHARMACY Comments Off on Drug therapy in special situations

Fig. 56.1 Sales of thalidomide and the incidence of phocomelia.Thalidomide sales and phocomelia incidence are each expressed as a percentage of the reported maximum. The list of drugs known to…

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Cardiac arrhythmias

Jun 21, 2016 by in PHARMACY Comments Off on Cardiac arrhythmias

Fig. 8.1 Action potentials show variations in patterns among different populations of myocytes in different regions of the heart. The patterns are determined by the opening and closing of selective…

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Lipid disorders

Jun 21, 2016 by in PHARMACY Comments Off on Lipid disorders

Fig. 48.1 Major pathways in lipoprotein formation and metabolism.Dietary lipids including cholesterol (CHOL) and free fatty acids (FFA) in the gut are emulsified by bile acids and transported within chylomicrons…

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Androgens, anti-androgens and anabolic steroids

Jun 21, 2016 by in PHARMACY Comments Off on Androgens, anti-androgens and anabolic steroids

 sexual differentiation in the fetus,  sexual development of the male testis, penis, epididymis, seminal vesicles and prostate at puberty, and maintenance of these tissues in adults,  spermatogenesis in adults,  stimulation…

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The immune response and immunosuppressant drugs

Jun 21, 2016 by in PHARMACY Comments Off on The immune response and immunosuppressant drugs

 physicochemical barriers, e.g. intact skin and mucous membrane, low stomach pH, antibacterial agents (lysozyme) in skin and tear secretions,  macrophages and dendritic cells, particularly in lungs, liver, lymph nodes and…

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