Abstract Spermatozoa, one of the two most pivotal cells of biological existence, are responsible for mediating the transfer of genetic information to subsequent generations. Mammalian fertilization and subsequent embryonic development…
Abstract Seminal oxidative stress (OS) is a condition where the levels of oxidants overwhelm those of the antioxidants (reductants) present in the semen [1]. The most important oxidants are reactive…
Abstract Infertility is a difficult and stressful condition that impacts about 15 percent of couples attempting to conceive for the first time [1]. In about half of these cases a…
Abstract The incidence of infertility is up to 20–25 percent in men with poor semen quality with a contribution of the male factor in 30–50 percent of couples undergoing assisted…
Abstract Today, about 10–15 percent of couples at reproductive age worldwide are infertile and they are unable to conceive naturally without medical assistance. Infertility can be caused by male-only factors,…
Abstract Fertilization is an exceptionally specific cell recognition event that represents the culmination of a complex sequence of morphological and functional maturational events. In the case of the male gamete,…
Abstract Mitochondria are crucial organelles of eukaryotic aerobic cells (somatic and germ cells) because they produce adenosine triphosphate (ATP) and are modulators of ion homeostasis, generators of free radicals and…
Abstract The evaluation of sperm morphology as a standard procedure to be included in routine semen analysis is under persistent pressure due to several factors relating inter alia to the…
Abstract The acrosome reaction (AR) is an essential process of spermatozoa for fertilization and is characterized by the exocytosis of the acrosomal content and the release of hybrid membrane vesicles…
Abstract The hypo-osmotic swelling (HOS) test, introduced in 1987 to assess the functional integrity of the human sperm membrane, appears to have withstood the test of time. Many articles have…
