Molecular Pathology of Solid Tumors
Tumor Cytogenetic alteration Fusion genes [significance] Alveolar rhabdomyosarcoma t(2;13)(q35;q14) PAX3–FOXO1(FKHR) Alveolar rhabdomyosarcoma t(1;13)(p36;q14) PAX7–FOXO1(FKHR) – [favorable prognosis] Alveolar soft part sarcoma t(X;17)(p11;q25) TFE3–ASPSCR1(ASPL) – [sensitive to MET inhibitors] Clear cell…