Histoplasmosis Key Facts Terminology Disease caused by inhalation of the fungus Histoplasma capsulatum Clinical Issues Clinical forms of histoplasmosis include benign self-limited, acute, chronic, progressive disseminated, and with mediastinal involvement…
Tuberculosis Key Facts Terminology Lung infection caused by inhalation of Mycobacterium tuberculosis Clinical Issues Primary infection usually asymptomatic and leads to formation of the Ghon complex (apical nodule with calcification)…
Eosinophilic Pneumonia Key Facts Terminology Synonyms Loeffler syndrome Definition Patchy pulmonary infiltrates characterized by presence of eosinophils as main inflammatory component Etiology/Pathogenesis Parasites Ingestants and inhalants Fungal infections Drug toxicity…
Protocol for Malignant Pleural Mesothelioma Specimen Examination Pleura: Resection Surgical Pathology Cancer Case Summary (Checklist) Specimen ____ Pleura ____ Other (specify): ______________________________ ____ Not specified Procedure ____ Pleural decortication ____…
Nocardiosis Key Facts Etiology/Pathogenesis Nocardia asteroides Aerobic, partially acid-fast branching actinomycete Rarely measures > 1 µm in diameter Other types of Nocardia may also be the pathogenic agent Clinical Issues…
SARS Pneumonia Key Facts Terminology Severe acute respiratory syndrome (SARS) Etiology/Pathogenesis Etiological agent SARS coronavirus (SARS-CoV) SARS can be transmitted by Direct contact Droplet Airborne route Clinical Issues Symptomatology Flu-like…
Cryptococcosis Key Facts Terminology Lung infection caused by inhalation of Cryptococcus neoformans spores Clinical Issues Acute pulmonary infection can be asymptomatic or self-limited Progressive infection is seen in immunocompromised hosts…
Actinomycosis Key Facts Etiology/Pathogenesis Actinomyces israelii Common saprophyte of the mouth and tonsils Other types isolated from infections include A. naeslundii A. propionicus A. eriksonii Clinical Issues May involve the…
Asbestos-related Interstitial Fibrosis Key Facts Terminology Asbestosis Interstitial pulmonary fibrosis secondary to inhalation of asbestos dust Etiology/Pathogenesis 2 types of asbestos fibers have been identified Serpentine Chrysotile (more common in…
Metastatic Carcinoma Key Facts Clinical Issues Cough, chest pain, dyspnea, hemoptysis, and pleural effusion are most common presenting symptoms Most common primary sites: Genital, gastrointestinal and genitourinary tracts, pancreatohepatobiliary tract,…
