Mesenchymal Chondrosarcoma

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Mesenchymal Chondrosarcoma

Mesenchymal Chondrosarcoma Key Facts Clinical Issues Extremely rare tumor Predilection for young adults (15-35 years) Slight female predilection Incidental finding on routine chest x-rays Aggressive malignancy Approximately 50% 5-year survival…

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Malignant Mesothelioma

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Malignant Mesothelioma

Malignant Mesothelioma Key Facts Etiology/Pathogenesis Mesotheliomas have been linked closely to asbestos exposure Clinical Issues Rare tumor that accounts for approximately 4-7 cases per 1,000,000 individuals Tumor is more common…

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MALT Lymphoma of the Thymus

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on MALT Lymphoma of the Thymus

MALT Lymphoma of the Thymus Key Facts Terminology Low-grade lymphoma derived from distinct native population of thymic postgerminal center stage parafollicular B cells Etiology/Pathogenesis Believed to represent thymic counterpart of…

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Solitary Fibrous Tumor

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Solitary Fibrous Tumor

Solitary Fibrous Tumor Key Facts Clinical Issues Asymptomatic; incidental finding on routine chest x-ray Cough Pleuritic pain Dyspnea Hypoglycemia (5% of patients) Pulmonary osteoarthropathy with clubbing of fingers Microscopic Pathology…

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Paraganglioma

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Paraganglioma

Paraganglioma Key Facts Terminology Synonyms Extraadrenal paraganglioma, carotid body tumor Clinical Issues Incidence May occur at any age More common in 3rd decade of life May occur in anterior and…

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Lymphoblastic Lymphoma

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Lymphoblastic Lymphoma

Lymphoblastic Lymphoma Key Facts Etiology/Pathogenesis Neoplastic proliferation of blastic precursor lymphocytes Clinical Issues Occurs more commonly in children than in adults Anterior superior and middle mediastinum Rapidly enlarging mediastinal mass…

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Pleural Endometriosis

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Pleural Endometriosis

Pleural Endometriosis Key Facts Terminology Endometrioma, deciduosis Clinical Issues Incidence Unusual occurrence in thoracic cavity Predominantly in women of reproductive age May be seen in older postmenopausal women Symptoms Cough…

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Antibody Index

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Antibody Index

Antibody Index Antibodies Discussed Antibody Name/Symbol Antibody Description Clones/Alternative Names Chapters α-fetoprotein alpha 1 fetoprotein AFP, Z5A06, clone C3 Choriocarcinoma; Embryonal Carcinoma; Mediastinal Seminoma; Mediastinal Teratoma κ light chain kappa…

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Hemangioma

Jul 9, 2016 by in PATHOLOGY & LABORATORY MEDICINE Comments Off on Hemangioma

Hemangioma Key Facts Clinical Issues Rare tumor Affects broad age range, from newborns to old age More frequent in children and young adults Anterior and posterior mediastinum Some cases may…

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