Neuroendocrine Carcinoma (Including Small Cell Carcinoma) Key Facts Terminology Spectrum of neoplasms ranging from low- to high-grade malignancy Clinical Issues Paraneoplastic syndromes Macroscopic Features Endobronchial or intraparenchymal tumor 0.5 to…
Pulmonary BALT Hyperplasia Key Facts Terminology Polyclonal proliferation of small lymphocytes arising within lung parenchyma Etiology/Pathogenesis Commonly associated with underlying autoimmune disorders such as Sjögren syndrome, rheumatoid arthritis, and collagen…
Mixed Tumor Key Facts Terminology Synonym: Pleomorphic adenoma (PA) Biphasic neoplasm with epithelial/myoepithelial and mesenchymal differentiation Clinical Issues Symptoms Cough Dyspnea Chest pain Hemoptysis Prognosis Excellent for benign tumors Malignant…
Hodgkin Lymphoma Key Facts Clinical Issues HL arising primarily in lungs is extremely rare Pulmonary involvement is most often seen in course of regional or systemic dissemination Night sweats Mediastinal,…
Pulmonary Artery Sarcoma Key Facts Terminology Synonym: Intimal sarcoma Malignant mesenchymal tumor originating from wall of pulmonary trunk Clinical Issues Cough Chest pain Shortness of breath Fatigue Syncope Macroscopic Features…
Mucoepidermoid Carcinoma Key Facts Terminology Epithelial neoplasm composed of epidermoid and clear cells admixed with mucus-secreting cells (mucocytes) Clinical Issues Prognosis Depends on grading of tumor For low-grade tumors, prognosis…
Osteosarcoma Key Facts Terminology Malignant mesenchymal neoplasm with osseous differentiation Clinical Issues Incidence Osteosarcomas of lung are exceedingly rare with > 30 cases reported Pulmonary osteosarcomas appear to be more…
Angiosarcoma Key Facts Terminology Hemangiosarcoma Clinical Issues Symptomatology Shortness of breath Hemoptysis Frank pulmonary hemorrhage Macroscopic Features Single or multiple pulmonary nodules Microscopic Pathology Epithelioid malignant cells forming vascular channels…
Chrondrosarcoma Key Facts Terminology Malignant mesenchymal neoplasm with cartilaginous differentiation Clinical Issues Incidence Primary chondrosarcomas of lung are exceedingly rare More common in 6th and 7th decades of life Can…
Epi-myoepithelial Carcinoma Key Facts Terminology Adenomyoepithelioma, epithelial-myoepithelial tumor, epithelial-myoepithelial tumor of unknown malignant potential, pneumocytic adenomyoepithelioma Clinical Issues Cough Chest pain Hemoptysis Macroscopic Features Endobronchial tumor 2.5-5 cm in greatest…
