Ganglioneuroblastoma
Ganglioneuroblastoma Key Facts Terminology P-GNB Clinical Issues Incidence GNBs are exceedingly rare tumors in the lung Cases described have been in adult patients There is no gender predilection Symptoms Cough…
Juvenile Xanthogranuloma
Juvenile Xanthogranuloma Key Facts Terminology Abbreviation: Pulmonary juvenile xanthogranuloma (JXG) Definition Non-Langerhans histiocytic lesion Etiology/Pathogenesis Contrary to other histiocytic lesions, cell of origin for JXG is unknown Plasmacytoid monocyte has…
Angiolymphoid Hyperplasia with Eosinophilia
Angiolymphoid Hyperplasia with Eosinophilia Key Facts Terminology Angiolymphoid hyperplasia with eosinophilia (ALHE) Epithelioid hemangioma Clinical Issues Presentation Cough Dyspnea Asthma Treatment of choice: Complete surgical resection Lobectomy Wedge resection Prognosis:…
Inflammatory Pseudotumor
Inflammatory Pseudotumor Key Facts Terminology Myofibroblastic tumor Etiology/Pathogenesis Some cases linked to HHV-8 Clonality demonstrated in some cases Clinical Issues Tumor more common in young individuals < 40 years old…
Lymphomatoid Granulomatosis
Lymphomatoid Granulomatosis Key Facts Terminology Angiocentric lymphoproliferative disorder composed of Epstein-Barr-infected B cells admixed with reactive T cells Clinical Issues Cough Dyspnea Microscopic Pathology Sheets of mixed, polymorphous atypical lymphoreticular…
Plasmacytoma
Plasmacytoma Key Facts Clinical Issues Incidence Primary plasmacytomas of lung are rare May represent approximately 5% of all extramedullary plasmacytomas Tumor has been described essentially in adults Symptoms Cough Hemoptysis…
Atypical Adenomatous Hyperplasia
Atypical Adenomatous Hyperplasia Key Facts Terminology Microscopic proliferation of atypical alveolar lining cells measuring < 5 mm in greatest diameter Clinical Issues Incidental microscopic finding in lung tissues removed for…
Pulmonary BALT Lymphoma
Pulmonary BALT Lymphoma Key Facts Clinical Issues Most common presentation is solitary mass on routine imaging studies Most patients are asymptomatic Favorable prognosis; 5-year survival in approximately 85-95% Image Findings…
Bronchial Malignant Melanoma
Bronchial Malignant Melanoma Key Facts Clinical Issues Incidence Approximately 0.01% of all lung neoplasms More common in adults in 6th decade of life Symptoms Cough Dyspnea Chest pain hemoptysis Fever…
IgG4 Sclerosing Lung Disease
IgG4 Sclerosing Lung Disease Key Facts Terminology Systemic disease of unknown etiology characterized by elevated production of IgG4(+) plasma cells and tissue stromal sclerosis Clinical Issues Slowly progressive disease with…
