Lymphomas Associated with FGFR1 Abnormalities Roberto N. Miranda, MD Key Facts Terminology Lymphoblastic lymphoma occurring in patients with 8p11 myeloproliferative syndrome EMS is aggressive disease associated with FGFR1 gene abnormalities;…
B-cell Lymphoma, Unclassifiable, with Features Intermediate Between Diffuse Large B-cell Lymphoma and Classical Hodgkin Lymphoma Francisco Vega, MD, PhD Key Facts Terminology B-cell lymphoma, unclassifiable, with features intermediate between DLBCL…
Langerhans Cell Sarcoma Sa A. Wang, MD Key Facts Terminology Neoplastic proliferation of Langerhans cells with overtly malignant cytologic features Clinical Issues LCS most often presents as de novo mass…
Primary Mediastinal (Thymic) Large B-cell Lymphoma Francisco Vega, MD, PhD Key Facts Terminology Diffuse large B-cell lymphoma (DLBCL) arising in mediastinum of putative thymic B-cell origin Clinical Issues Most frequent…
Angioimmunoblastic T-cell Lymphoma Sa A. Wang, MD Key Facts Terminology Peripheral T-cell lymphoma derived from CD4(+) follicular helper T cells characterized by Lymphadenopathy, systemic disease, and, usually, immunodysregulation and immunodeficiency…
Lymphoplasmacytic Lymphoma and Waldenstrom Macroglobulinemia Pei Lin, MD Key Facts Terminology LPL is a neoplasm of small B lymphocytes ± plasmacytoid features and plasma cells that does not meet criteria…
Interdigitating Dendritic Cell Sarcoma Wesley O. Greaves, MD L. Jeffrey Medeiros, MD Key Facts Clinical Issues Wide age range Single lymph nodes most commonly involved Cervical, axillary, or inguinal groups…
T-cell Prolymphocytic Leukemia Involving Lymph Node and Other Tissues Tariq Muzzafar, MBBS L. Jeffrey Medeiros, MD Key Facts Terminology T-PLL is aggressive disease characterized by Numerous small/medium-sized T prolymphocytes Involvement…
Primary Diffuse Large B-cell Lymphoma of the CNS Tariq Muzzafar, MBBS Key Facts Clinical Issues Neuropsychiatric signs and symptoms Raised intracranial pressure Intraocular involvement: blurred vision and floaters Image Findings…
Angiomyomatous Hamartoma Carlos E. Bueso-Ramos, MD, PhD Key Facts Terminology Benign smooth muscle proliferation that begins in hilum and extends into medulla and cortex of lymph node Involves inguinal lymph…
