Basicmedical Key

Malignant Melanoma, Vagina C. Blake Gilks, MD, FRCPC Key Facts Clinical Issues < 3% of malignant tumors of vagina Peri- and postmenopausal ages (mean: 57 years) Distal 1/3 (anterior) of…

Yolk Sac Tumor, Vagina C. Blake Gilks, MD, FRCPC Esther Oliva, MD Key Facts Clinical Issues Children < 3 years Painless vaginal mass, may prolapse through introitus Combination chemotherapy associated…

Vaginal Intraepithelial Neoplasia C. Blake Gilks, MD, FRCPC Key Facts Clinical Issues More common > 40 years (peak: 60-70) Frequent history of HPV-associated CIN, VIN, or cervical or vulvar squamous…

Ligneous Vaginitis Marisa R. Nucci, MD Key Facts Etiology/Pathogenesis Inherited type I plasminogen deficiency Clinical Issues Degree and extent of associated clinical symptoms and signs not predictable Microscopic Pathology Subepithelial…

Desquamative Inflammatory Vaginitis Marisa R. Nucci, MD Key Facts Terminology Inflammatory vaginitis with marked inflammation and sloughing of epithelium Etiology/Pathogenesis Unknown, may be autoimmune or may represent form of erosive…

Atypical Nevus of the Genital Tract Russell Ball, MD Marisa R. Nucci, MD Key Facts Terminology Benign melanocytic proliferation with architectural and cytologic features that differ from common nevi and…

Malignant Melanoma, Vulva Maria Angelica Selim, MD Key Facts Clinical Issues Predominantly postmenopausal Mass, bleeding, discharge, pruritus, pain ˜ 30% amelanotic, especially mucosal surfaces Macroscopic Features Macule or plaque with…

Extramammary Paget Disease Maria Angelica Selim, MD Russell Ball, MD Key Facts Terminology Intraepidermal adenocarcinoma (primary or secondary) with frequent extension into adnexal structures; rarely invasive Clinical Issues Often, clinically…

Fibroepithelial Stromal Polyp Marisa R. Nucci, MD Key Facts Clinical Issues More common during pregnancy Vulva, vagina, and rarely cervix Local excision Macroscopic Features Usually < 5 cm Typically polypoid…