Invasive Urothelial Carcinoma Jesse K. McKenney, MD Key Facts Terminology Urothelial carcinoma that invades beyond basement membrane Clinical Issues Invasion into lamina propria usually managed with intravesical therapy Invasion into…
Cystitis Cystica and Glandularis Jesse K. McKenney, MD Key Facts Terminology Invaginated urothelial nests in superficial lamina propria with cystic dilatation forming luminal space Cystitis glandularis has luminal cuboidal or…
High-Grade Papillary Urothelial Carcinoma Jesse K. McKenney, MD Mahul B. Amin, MD Key Facts Terminology Papillary urothelial neoplasm with moderate to marked nuclear atypia Clinical Issues Most occur in 6th…
Adenocarcinoma In Situ Jesse K. McKenney, MD Key Facts Terminology Noninvasive glandular lesion characterized by atypical columnar epithelium Also called “noninvasive urothelial carcinoma with glandular differentiation” and “urothelial carcinoma with…
Low-Grade Papillary Urothelial Carcinoma Jesse K. McKenney, MD Mahul B. Amin, MD Key Facts Terminology Papillary urothelial neoplasm with some degree of cytoarchitectural disorder and distinct but low-grade cytologic abnormality…
Villous Adenoma Jesse K. McKenney, MD Key Facts Terminology Benign glandular neoplasm arising from urothelium Clinical Issues Presenting symptoms Hematuria and irritative bladder symptoms Rarely, mucosuria can be seen Therapy:…
Inverted Papilloma Jesse K. McKenney, MD Key Facts Terminology Benign urothelial neoplasm with predominantly endophytic growth pattern Clinical Issues Very uncommon urothelial lesion (1% of urothelial neoplasms) Most common in…
Overview of Urinary Bladder Neoplasms Jesse K. McKenney, MD Mahesha Vankalakunti, MD The spectrum of neoplasia in the bladder includes noninvasive papillary urothelial carcinomas. These may progress to invasive urothelial…
Nephrogenic Adenoma Jesse K. McKenney, MD Mahul B. Amin, MD Key Facts Etiology/Pathogenesis Many are secondary to urothelial injury Clinical Issues Usually incidental microscopic findings May have irritative symptoms from…
Amyloidosis Jesse K. McKenney, MD Key Facts Terminology Deposition of amyloid protein in urinary bladder 2 types Primary localized process Systemic amyloidosis Microscopic Pathology Deposition of eosinophilic amorphous material in…
