Basicmedical Key

Fibrous Obliteration Scott R. Owens, MD Key Facts Terminology Fibrosing process → loss of normal mucosal and lymphoid structures, may occlude appendiceal lumen Etiology/Pathogenesis Many associated with neural proliferations (“neuromas”)…

Waldenstrom Protein Scott R. Owens, MD Key Facts Etiology/Pathogenesis Often associated with lymphoplasmacytic lymphoma (LPL) Clinical Issues Diarrhea and malabsorption may lead to intestinal biopsy Microscopic Pathology Dilated mucosal lymphatics…

Carcinoid Joel K. Greenson, MD Key Facts Clinical Issues Carcinoid syndrome (< 10% of patients) Most often asymptomatic incidental finding 2/3 of patients with carcinoid syndrome get fibrous endocardial thickening…

Gangliocytic Paraganglioma Elizabeth A. Montgomery, MD Key Facts Clinical Issues Overwhelming majority in duodenum Benign in majority of cases Rare reports of regional metastases No reports of tumor-associated deaths Microscopic…

Mycobacterium tuberculosis Laura W. Lamps, MD Key Facts Clinical Issues GI symptoms, rather than pulmonary, may be initial presentation Macroscopic Features Frequency of involvement: Ileocecum > jejunoileum > appendix >…

Yersinia Laura W. Lamps, MD Key Facts Etiology/Pathogenesis Common food- and water-born gastrointestinal infection Image Findings May mimic acute appendicitis or Crohn disease May show nonspecific features of enterocolic inflammation…

Pouchitis Joel K. Greenson, MD Key Facts Clinical Issues Acute pouchitis may be due to bacterial overgrowth and respond to antibiotics Chronic relapsing pouchitis that does not respond to antibiotics…

Autoimmune Enterocolitis Joel K. Greenson, MD Key Facts Terminology Rare form of intractable diarrhea secondary to enteropathy associated with autoantibodies Clinical Issues Anti-enterocyte antibodies: Indirect immunofluorescence using patients’ serum against…

Primary Lymphangiectasia Joel K. Greenson, MD Key Facts Clinical Issues Presentation is often within 1st 3 years of life, although some patients present later Decreased serum albumin, protein, and gammaglobulins…

Necrotizing Enterocolitis Joel K. Greenson, MD Key Facts Etiology/Pathogenesis Hyperosmolar feedings increase risk of disease Bacterial colonization also seems to play a role Clinical Issues Death secondary to sepsis from…