Crohn Disease Alexandros D. Polydorides, MD, PhD Key Facts Terminology IBD discontinuously involving upper or lower GI Etiology/Pathogenesis Environmental trigger in genetically predisposed individuals leads to immunologically mediated injury Clinical…
Salmonella Laura W. Lamps, MD Key Facts Terminology Transmitted through contaminated food and water Generally divided into 2 groups: Typhoid and nontyphoid species Clinical Issues Fever Abdominal pain Diarrhea Macroscopic…
Pneumatosis Coli Sharon K. Bihlmeyer, MD Key Facts Terminology Synonym: Pneumatosis cystoides intestinalis Presence of gas in bowel wall Clinical sign of underlying disease process rather than disease entity itself…
Campylobacter Laura W. Lamps, MD Key Facts Terminology Most common stool isolate in United States Clinical Issues Diarrhea Abdominal pain Infants, children, and young adults most commonly affected Higher incidence…
Diverticular Disease-related Colitis Sharon K. Bihlmeyer, MD Key Facts Terminology Ulcerative colitis-like variant (chronic segmental colitis in distribution of diverticula) Crohn-like variant (Crohn-like reaction to diverticulitis in resection specimen) Clinical…
Solitary Rectal Ulcer Syndrome/Mucosal Prolapse Julianne K. Purdy, MD Key Facts Clinical Issues Rare; usually in young to middle-aged adults Ulcer, polyp, erythema on anterior rectal wall Rectal bleeding or…
Lymphocytic Colitis Julianne K. Purdy, MD Key Facts Clinical Issues Middle-aged to elderly individuals Less pronounced female predominance than in collagenous colitis (CC); M:F = 1:1-5.7 Chronic nonbloody diarrhea More…
Mastocytosis Sharon K. Bihlmeyer, MD Key Facts Terminology Systemic mastocytosis involves multiple organs (usually bone marrow) ± skin Clinical Issues Abdominal pain and diarrhea Systemic and gastrointestinal symptoms secondary to…
Collagenous Colitis Julianne K. Purdy, MD Key Facts Clinical Issues Middle-aged to elderly women Chronic nonbloody diarrhea Normal colonoscopy Microscopic Pathology Patchy subepithelial increased collagen Most reliable biopsies from transverse…
Ulcerative Colitis, Colon Scott R. Owens, MD Key Facts Terminology Chronic, idiopathic, remitting, and relapsing inflammatory disease Part of spectrum of inflammatory bowel disease (IBD) Clinical Issues Rectum usually involved…
