Basicmedical Key

Pretest self-assessment question (answer at the end of the case) What pharmacologic properties of quetiapine (Seroquel) lend themselves to providing clinical antidepressant and anxiolytic properties? A. 5-HT1A partial receptor agonism…

Pretest self-assessment question (answer at the end of the case) A 55-year-old patient with depression has the S/S genotype for the SERT gene (SLC6A4). Based only on this genetic result,…

Pretest self-assessment question (answer at the end of the case) What is the evidence to support the use of clonazepam (Klonopin) in manic patients? A. It is not approved but…

Pretest self-assessment question (answer at the end of the case) A 54-year-old patient has depression with prominent cognitive symptoms and also has the Val/Val genotype for catechol-O-methyltransferase (COMT). Based only…

Pretest self-assessment question A 23-year-old patient with her first depression has the S/S genotype for the SERT gene, the Del/Del alleles for the D2 receptor gene, the Val/Val alleles for…

Pretest self-assessment question (answer at the end of the case) Which are correct regarding vascular depression? A. There is evidence that cerebrovascular disease creates vulnerability to depression, as well as…

Pretest self-assessment question (answer at the end of the case) Clozapine (Clozaril)-induced sialorrhea (CIS), or excessive drooling, is caused by what theoretical pharmacologic mechanism? A. Dopamine-2 receptor antagonism B. Alpha-2…