3.  A subtotal pancreatic resection is performed in a patient with malabsorption. The histopathologic changes are shown in this picture. There is apparent hyperplasia of the islets of Langerhans. Which of the following is the most common complication of this condition?

  4.  A 69-year-old man presents with chronic diarrhea, steatorrhea, weight loss, and painless jaundice. A CT scan reveals diffuse, sausage-shaped enlargement of the pancreas with narrowing of the main duct. His serum IgG4 level is elevated. Out of concern for possible cancer, a biopsy of the pancreas is performed, revealing the histologic changes shown in this picture. Also, the inflammatory reaction is noted to involve veins, producing a picture of obliterative phlebitis. Which of the following is the most likely diagnosis?

  5.  This photomicrograph shows a specific histologic change in a pancreatic biopsy from a patient thought to have autoimmune pancreatitis (AIP). Which of the following types of AIP does this patient have?

  6.  A pancreatic ductal adenocarcinoma (PDAC) shows the microscopic features highlighted in this picture. Which variant of PDAC is this?

  7.  An ultrasound-guided FNA of a pancreatic lesion reveals the cell clusters shown in this picture. Which of the following is the most likely diagnosis?

  8.  All of the following features are helpful in the differential diagnosis between PDAC and benign noninvasive ducts, EXCEPT:

  9.  This photomicrograph shows the FNA of a pancreatic mass. Which of the following is the most likely diagnosis?

10.  Which of the following histologic types of pancreatic carcinoma is associated with microsatellite instability (MSI)?

11.  A pancreatic tumor shows a mixture of different neoplastic components including areas that appear as in this low-power picture admixed with areas of glandular differentiation. There are large cells with bizarre multilobulated nuclei and atypical mitotic figures. Which of the following features is characteristic of this neoplasm?

12.  Which of the following types of PanIN is most commonly found with a coexisting invasive ductal adenocarcinoma?

13.  This photomicrograph shows a lesion that was removed from the head of the pancreas in a patient who suffered from acute pancreatitis. Which of the following is the most likely diagnosis?

14.  The multiloculated cystic tumor shown in this picture is almost exclusively found in perimenopausal women. Which one is it?

15.  A pancreatic tumor is found at the autopsy of a 75-year-old woman who died of a myocardial infarction. On the cut surface, the tumor shows small cysts filled with serous fluid. Histologically, the septa between cysts are lined by cuboidal cells with clear cytoplasm and contain scattered islets of Langerhans. Which of the following is the most likely diagnosis?